he adenomatoid odontogenic tumor (AOT) is a clinically benign lesion. Discussions about the AOT hamartomatous or neoplastic nature, and the probable odontogenic epithelial cell it originates from still exist. This research aimed to study and discuss the subject by the immunohistochemical detection of cytokeratins, laminin, collagen IV, PCNA and p53 in 8 tumor samples and 8 dental follicle sampl...

Odontogenic myxoma is a rare and locally invasive benign neoplasm found exclusively in jaws. It presents local invasiveness and tendency to recurrence. According to the World Health Organization (WHO), the odontogenic myxoma is classified as an odontogenic tumor of ectomesenchymal origin. The odontogenic myxoma is a rare entity found in both jaws while the mandible is involved more commonly tha...

central granular cell odontogenic tumor) cgcot) of the jaw is an exceedingly rare benign odontogenic neoplasm with 35 reported cases in the literature. among these, very few studies have focused on the cone-beam ct features of cgcot. here, we report a case of an asymptomatic cgcot in a 16-year-old girl and focus on the cone-beam ct features. only 36 cases of this lesion, including this one, hav...

keratocystic odontogenic tumor (kcot) is a benign intraosseous neoplasm of the jaw occurring most commonly in mandibular ramus molar area with male predilection. peripheral kcots are very uncommon. here we report a case of keratocyst in buccal mucosa in a 55 years old female patient, the diagnosis of which was based on subjective histological evaluation and further confirmed by immunohistochemi...

adenoid ameloblastoma with dentinoid is a rare odontogenic tumor. granular cell ameloblastoma also is a less common histological subtype of ameloblastoma. in this report, the patient was a 31‑year‑old male. the lesion was located in the right mandible and was unicystic with well‑defined borders. the tumor tissue was showing a combination of follicular, plexiform, and desmoplastic patterns of am...

Odontogenic carcinosarcoma is an extremely rare malignant odontogenic tumor with only a few reported cases. It is characterized by a true mixed tumor showing malignant cytology of both epithelial and mesenchymal components. It has been assumed to arise from pre-existing lesions such as ameloblastoma, ameloblastic fibroma, and ameloblastic fibrosarcoma. To date, the reported cases have exhibited...

background: odontogenic keratocyst (okc), also called keratocystic odontogenic tumor (kcot), is a developmental lesion which should be carefully monitored and it exhibits development mechanisms and biologic behaviors different from those of other more common lesions such as dentigerous and radicular cysts. cd10 antigen is a cell surface metalloendopeptidase, which inactivates various peptides t...

Odontogenic tumor is one of the tumors of great significance in the oral region. The process of its development remains obscure. It seems very advantageous in the investigation of dontogenic tumor to establish experimental models in laboratory animals. However, experimental attempts of induction of odontogenic tumor have not been very successful. In recent years, the carcinogenic property of ni...

The calcifying odontogenic cyst (COC) is a rare odontogenic cyst. Only 2% of all odontogenic cysts and tumors are COC. COC associated with odontoma (COCaO) reported in 24% of COCs. COCaO presents a greater incidence in female, with a ratio of 2 to 1. The highest incidence of COCaO occurs during the second decade with a mean age of 16 years, most frequently occurring in the maxilla (61.5%). Here...

Odontogenic tumors and cysts, arising in the jawbones, grow by resorption and destruction of the jawbones. However, mechanisms underlying bone resorption by odontogenic tumors/cysts remain unclear. Odontogenic tumors/cysts comprise odontogenic epithelial cells and stromal fibroblasts, which originate from the developing tooth germ. It has been demonstrated that odontogenic epithelial cells of t...