It was the purpose of this study to evaluate dental age in boys with delayed puberty and to compare them with a group of normal, healthy boys. The study group consisted of eight boys with constitutional delay of growth and puberty (CDGP), older than 14 years, and with a testis volume smaller than 4 ml. The control group comprised 38 normal, healthy boys, aged between 12.4 and 14.3 years. Dental...

Dens invaginatus is a developmental anomaly resulting from invagination of a portion of crown forming within the enamel organ during odontogenesis. The invagination ranges from a slight pitting (coronal type) to an anomaly occupying most of the crown and root (radicular type). Although a clinical examination may reveal a deep fissure or pit on the surface of an anterior tooth, radiographic exam...

* DDS, MSc, PhD. Assistant Professor of Orthodontics. Rehabilitation Hospital of Craniofacial Anomalies, Bauru Dental School, University of São Paulo Bauru/SP, Brazil. ** Master of Orthodontics, São Paulo City University (Unicid), São Paulo/SP, Brazil. *** Head of the Masters Course in Orthodontics of the São Paulo City University, Unicid, São Paulo/SP, Brazil. **** Professor of the Postgraduat...

Odontogenic lesions can be divided discretely into cysts (an epithelial lined pathological cavity) and tumors (a solid tissue mass, not necessarily neoplastic). They are derived from tooth forming tissues, either the epithelial or the ectomesenchymal or both. They form a heterogeneous group of hamartomatous lesions, benign and malign tumors. According to their origins, they are divided into epi...

The transcription factor Ctip2/Bcl11b plays essential roles in developmental processes of the immune and central nervous systems and skin. Here we show that Ctip2 also plays a key role in tooth development. Ctip2 is highly expressed in the ectodermal components of the developing tooth, including inner and outer enamel epithelia, stellate reticulum, stratum intermedium, and the ameloblast cell l...

The interruption of odontogenesis by any etiological factor may result in dental anomalies. Apart from the environmental factors, the impact of genetics in dental anomalies was found to be a factor in different levels. Many authors had questioned a common genetic defect resulting in different phenotypic conditions such as absent, malformed, malposed or ectopic teeth. Because the multidisciplina...

Expression pattern of Irx1 and Irx2 during mouse digit development 159 C. Barrett, S. Guthrie (UK) Expression patterns of the netrin receptor UNC5H1 among developing motor neurons in the embryonic rat hindbrain 163 Embryonic expression of Kru Èppel-like factor 6 in neural and non-neural tissues 167 Dynamic expression patterns of the new protocadherin families CNRs and Pcdh-g during mouse odonto...