Background: The practice of self-medication has been recognized since ages. There has been enough literature available regarding it being there for medical illnesses, however, there is dearth of information about it for dental causes. Hence, this study was designed to determine the abuse of self-medication for dental illnesses and the reasons for resorting to it. Methods: This study was conduct...

Langerhans cell histiocytosis (LCH) is a rare disease, of unknown pathogenesis, characterized by intense and abnormal proliferation of bone marrow-derived histiocytes (Langerhans cells). It can present both local and systemic manifestations involving bone, skin and mucosal tissue, and internal organs. Three basic clinical forms develop: Letterer-Siwe disease (subacute or acute disseminated form...

OBJECTIVE To examine the use of intravenous immunoglobulin (i.v.i.g.) in chronic pain. DESIGN A prospective multiple-dose, open-label cohort study in 130 consecutive patients who suffered from 12 chronic pain syndromes. The largest symptom groups were (number of patients): Fibromyalgia (48); Spinal pain (20); Complex regional pain syndrome (CRPS, 11); Peripheral neuropathic pain (12); and Aty...

Chronic orofacial pain is a symptom associated with a wide range of neuropathic, neurovascular, idiopathic, and myofascial conditions that affect a significant proportion of the population. While the collective impact of the subset of the orofacial pain disorders involving neurogenic and idiopathic mechanisms is substantial, some of these are relatively uncommon. Hence, patients with these diso...

Structural changes in symbiotic human microorganisms can affect host phenotype. Liver-fire hyperactivity syndrome (LFHS) presents as bitter taste, halitosis, xerostomia, odontalgia, and other oral symptoms. LFHS is associated with hypertension (EH). In this study, tongue flora was analyzed to further understand the intrinsic relationship between tongue flora and LFHS. Samples of tongue coating,...

IMPORTANCE OF THE FIELD Although trigeminal neuralgia has traditionally been considered the prime neuralgic condition in the face region, other forms of neuropathic pain are now being more frequently recognized and require recognition and a different management approach. AREAS COVERED IN THIS REVIEW This review principally covers medical management of trigeminal neuralgia; but also included i...

Root ofPlumbago indica Linn is used in ayurveda and siddha medicine for the treatment of colic inflammations bronchitis, helminthiasis, hemorrhoids, elephantiasis, hepatosplenomegaly, amenorrhea, odontalgia, piles, and diabetes. The present study aims to investigate the anatomical characters of thin and thick root and to confirm the physicochemical characters of the root. Anatomical st...

BACKGROUND To determine the clinical characteristics of Continuous Neuropathic Orofacial Pain in patients that suffer Persistent Idiopathic Facial Pain (PIFP), Painful Post-Traumatic Trigeminal Neuropathy (PPTTN) or Burning Mouth Syndrome (BMS) and to describe their treatment. MATERIAL AND METHODS A retrospective observational study was made, reviewing the clinical history of the patients dia...

ton VA Medical Center, Houston, TX published findings from their randomized, controlled trial demonstrating that sham arthroscopic surgery is as effective as arthroscopic lavage or arthroscopic debridement in treating osteoarthritis of the knee.1 According to the researchers, the cost of such surgeries exceeds $3 billion a year in the United States alone.1 Beyond the specific implications for p...

OBJECTIVES Our specific aim in 49 patients (42 women, 7 men) with osteonecrosis of the jaw was to determine whether thrombophilia (increased tendency to intravascular thrombosis) or hypofibrinolysis (reduced ability to lyse thrombi) were associated with this regional avascular necrosis. STUDY DESIGN Determinants of thrombosis and fibrinolysis were compared in healthy controls and in 42 women ...