the ellis-van creveld (evc) syndrome is a chondroectodermal dysplasia and is characterized by the cardinal features of disproportionate short stature, polydactyly, hidrotic ectodermal dysplasia, and congenital heart malformations, along with other skeletal and dental abnormalities. it is a rare condition, with very few cases reported in the medical literature. it is inherited as an autosomal re...

early-onset diabetes, liver dysfunction, growth retardation, spondyloepiphyseal dysplasia, and tendency to skeletal fractures due to osteopenia are characteristics of wolcott-rallison syndrome (wrs). eukaryotic translation initiation factor 2α kinase (eif2ak3) is the only known gene, which is responsible for this rare autosomal recessive disorder. here, we report two siblings a girl and a boy w...

how to cite this article: shakiba m, nejad biglari h, alaee mr. digital and dental malformation and short stature in a patient with neurological problems: a variant of the oculodentodigital dysplasia syndrome or a new syndrome?iran j child neurol autumn 2012; 6(4): 51-54.   abstract several syndromes have been recognized with digital abnormality and cns involvement such as oculodentodigital dys...

background: although the imbalance of cytokines in head and neck squamous cell carcinoma (hnscc) is well known, there is scarce data regarding its occurrence during dysplasia, before the malignant transformation. objective: to determine whether laryngeal dysplasia patients show a different cytokine profile than patients with cancer and healthy controls. methods: seventeen newly diagnosed, untre...

About 80% of paediatric intractable epilepsy patients have accompanying cortical dysplasia. However, there are no established methods for noninvasive detection of cortical dysplasia. This paper proposes a novel method for automatically detecting cortical dysplasia using paediatric MR images. In order to evaluate cortical dysplasia in MR images, texture features and fractal dimension were extrac...

Ectodermal dysplasia, which affects ectodemal derivatives, currently is an X-linked recessive inheritary hypohydrotic ectodermal dysplasia. Patients with ectodermal dysplasia usually characterized by congenital teeth loss, abnormal teeth and inherited through female carriers. In this case report, we present a 5 years old boy of China ethnicity with mandibular anodontia, a rare dental dysplasia ...

Mongolia has high prevalence of H. pylori infection and gastric cancer. Early detection eradication can prevent the progression atrophy we reduce incidence cancer in our country. A Kyoto classification score 2 or more indicates a Endoscopic 4 might indicate risk. In this study compared consistency between advanced early cancer, grade dysplasia low-grade This is retrospective that included patie...

Current research highlighted the importance to recognize feasible biomarkers for early diagnoses and treatment in oral cancer. Our study analyzed expression spatial distribution of ALDH1A1, FGFR2, caspase-3, CD44 Oral Squamous Cell Carcinoma (OSCC) leukoplakia with without mucosal dysplasia. Paraffin-embedded samples OSCC (n=5), (n=5) dysplasia obtained by incisional biopsies were processed usi...

Since the original description by Taylor, the term focal cortical dysplasia has been used to refer to a wide range of alterations of the cortical mantle. More recently, these conditions have been described from neuroimaging, neuropathological and genetic standpoints, generating several classifications. It is widely recognized that these classifications are unsatisfactory. We propose a simplifie...

This study represents a multiplex cytokine analysis of serum from a 10-month randomized, controlled trial of 238 subjects that investigated the effects of selenomethionine and/or celecoxib in subjects with mild or moderate esophageal squamous dysplasia. The original chemoprevention study found that, among those with mild dysplasia, selenomethionine treatment favorably altered dysplasia grade. T...