Prime focus of the present investigation was to evaluate hepatoprotective potency of Ocimum sanctum (O. sanctum) aqueous extract against butyl p-hydroxybenzoic acid (butylparaben) toxicity in mice. Oral treatment of butylparaben (1320 mg/kg b.w./day) to mice for 30 days resulted in significant (p < 0.05) elevation in hepatic lipid peroxidation, which could be due to significant (p < 0.05) reduc...

Atherothrombotic diseases such as myocardial or cerebral infarction are serious consequences of the thrombus formed xin blood vessels. Thrombolytic agents are used to dissolve the already formed clots in the blood vessels; however, these drugs have certain limitations which cause serious and sometimes fatal consequences. Herbal preparations have been used since ancient times for the treatment o...

Effect of aqueous extracts of Ocimum sanctum and Camellia sinensis on restraint stress-induced oxidative damage in the central nervous system (CNS) of R. norvegicus were evaluated in terms of lipid peroxidation (LPO), reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT). Restraint stress was used for 3h/day for 6 days consecutively, caused a significant elevation in LPO and ...

Urinary tract infections are common type of pathogenic infections in body. Essential oils of Coleus aromaticus and two varieties of Ocimum sanctum (Rama Tulasi and Shyama Tulasi) were compared for antibacterial activity against urinary tract infection (UTI) causing bacteria; Staphylococcus aureus, Klebsiella oxytoca, Proteus vulgaris, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aerugin...

Introduction adaptogenic, immunomodulatory, free radical scavenging and antioxidant rejuvenating actions Irrational use of antibiotics as growth promoter (Shukla and Srivastava, 1999). The constituent herbs and as therapeutic agent or immunomodulator in of polyherbal formulation Stresroak which are livestock and poultry is current issue. International Phyllanthus emblica, Withania Somnifera, Ma...

BACKGROUND Essential Oils (EOs) possess antibacterial properties and represent a natural source to treat infections and prevent food spoilage. Their chemical composition might be affected by the environmental condition and the developmental growth stages of the plant. OBJECTIVES The current study aimed to determine the variations in chemical compositions and antimicrobial activities of the EO...

Administration of fresh leaves of Ocimum sanctum (Tulsi) mixed as 1 g and 2 g in 100 gms of diet given for four weeks, brought about significant changes in the lipid profile of normal albino rabbits. This resulted in significant lowering in serum total cholesterol, triglyceride, phospholipid and LDL-cholesterol levels and significant increase in the HDL-cholesterol and total faecal sterol conte...

Treatment with C. mukul and O. sanctum, showed a significant decrease in cholesterol and triglyceride levels respectively. O. sanctum also significantly increased serum HDL-cholesterol compared to control. Serum MDA levels were significantly reduced in all the treated groups compared to control suggesting that each of the drugs under study were effective in their free radical scavenging action....