BACKGROUND Although several studies have directly explored serotonin (5-HT) transmission in patients with obsessive-compulsive disorder (OCD), their results have been inconsistent and their clinical relevance is doubtful. METHOD According to a double-blind placebo-controlled design, plasma prolactin (PRL) response to a specific serotonergic probe, d-fenfluramine, was measured in 20 drug-free ...

BACKGROUND Patients with obsessive-compulsive disorder (OCD) frequently show poor social adjustment, which has been associated with OCD severity. Little is known about the effects that age at symptom onset, specific OCD symptoms, and psychiatric comorbidities have on social adjustment. The objective of this study was to investigate the clinical correlates of social functioning in OCD patients. ...

Obsessive-compulsive disorder (OCD) and attention-deficit and hyperactivity disorder (ADHD) frequently coexist. To understand whether childhood ADHD can increase the risk of OCD in adulthood and whether it influences the phenomenology of OCD, we investigated the symptoms of ADHD during childhood in obsessive-compulsive adults who had never been diagnosed as ADHD. Adults with OCD (n = 83) were g...

Introduction Obsessive-compulsive disorders are complex pathologies causing a major psychosocial handicap. However, their association with disabling somatic pathology such as rheumatoid arthritis makes management more difficult. Objectives To investigate through case analysis and review of literature the between obsessive-compulsive disorder (OCD) rheumatological disorders. Methods We reported ...

Gilles de la Tourette Syndrome (GTS) and obsessive-compulsive disorder (OCD) share obsessive-compulsive phenomena. The aims of this study were to compare the OC symptom distribution between GTS and OCD and to investigate whether a subdivision of these phenomena into obsessions, compulsions and 'impulsions' is useful in distinguishing GTS and OCD patients. Thirty-two GTS, 31 OCD (10 with tics, 2...

Previous studies have shown differences in clinical features of obsessive-compulsive disorder (OCD) between men and women, including mean age at onset of obsessive-compulsive symptoms (OCS), types of OCS, comorbid disorders, course, and prognosis. The aim of this study was to compare male and female patients with OCD on several demographic and clinical characteristics. All new patients with OCD...

most obsessive-compulsive disorder (ocd) patients meet psychiatrists 5 to 10 years after onset of ocd .its relatively high prevalence ratio and the delay in seeking help suggest that patients with ocd may seek help at non-psychiatric clinics. the present study was undertaken to provide some epidemiological data on the prevalence and severity of ocd in dermatological patients. the participants i...

The current study aimed to investigate the relationship of family environment and parental bonding with controlling compulsions (cc) obsessive compulsive disorder (OCD). also predictive value for OCD. Sample consisted 130 diagnosed patients OCD (65 males & 65 females) within age range 20-50 years. Three measures were used gather data - Family Environment Scale (FES), Parental Bonding Instru...

Obsessive Compulsive Disorder is one of the most disabling mental disorders in world and there are different interventions treatment strategy for obsessive compulsive disorder. A recent technique that has been gaining ground within positive psychology Mindfulness, this shown promising results being used as a new resource adherence to OCD symptoms. The aim study was perform systematic review lit...

ObjectiveObsessive-compulsive (OC) symptoms are common in the general population, but it is unclear whether subclinical OC and obsessive-compulsive disorder (OCD) part of a neuroanatomical continuum. The goal this study was to investigate relation between subcortical cortical morphology population-based sample children.MethodThe included 2,551 participants, aged 9–12 years, from Generation R St...