BACKGROUND Valvular aortic stenosis is a common disease in the elderly, often in multimorbid patients. It is often associated with coronary artery disease and peripheral artery disease. In this situation, the risk of conventional open-heart surgery is too high, and other treatment strategies have to be evaluated. CASE REPORT A 79-year-old female patient with severe aortic stenosis, coronary a...

Appropriate heart rate in a failing pulmonary ventricle remains unknown, particularly congenital disease with unique hemodynamics. A 71-year-old male repaired tetralogy of Fallot and pacemaker for sinus node dysfunction suffered from failure symptoms preserved left ventricular function. Simply changing the pacemaker’s lower 60 to 75 bpm, New York Heart Association classification improved III II...

Background and Objective: Chronic Obstructive Pulmonary Disease (COPD) is a chronic obstructive and irreversible disease which has a high mortality and morbidity rate. Systemic inflammation and the thrombotic process can influence the prognosis of these patients. The objectives of this study were to evaluate prognostic effects of CBC indices (WBC, PMN, MPV, RDW), forced expiratory volume-one se...

An elderly male patient with coronary heart disease underwent coronary angiography, which revealed bilateral severe coronary artery stenosis. Four stents were implanted, and at 5 h post-surgery, typical hemorrhagic shock appeared. Echocardiography verified heavy bleeding in the right thoracic cavity. Emergency angiography excluded injury or perforation of the coronary artery, aorta, right subcl...

Ten patients with chronic obstructive pulmonary disease without complicating cor pulmonale were studied by right and left heart catheterization. Respiratory and haemodynamic observations were made during a control period and during the infusion of phentolamine. Phentolamine produced a significant reduction in mean pulmonary artery pressure from I8 8 mmHg to I3 I mmHg, right ventricular end-dias...

abstract hypoplastic right ventricular is a rare congenital heart disease. a few cases have been reported. we presented a case with hypoplastic right ventricular and multiple associated anomaly (ventricular septal defect, atrial septal defect and pulmonary stenosis) in whom the main concern was whether biventricular repair or fontan type surgery would be the optimal management in this patient. ...

We banded the left pulmonary artery in rats to investigate, in the same animal, the effect of both increased and decreased flow on the lung vasculature and to determine how these hemodynamic states modify the structural changes produced by a 2-week exposure to hypobaric hypoxia. In unanesthetized rats, pressures were recorded from the main pulmonary artery and aorta via indwelling catheters, ca...

Pulmonary arterial hypertension (PAH) is a rare and severe clinical condition characterized by a progressive increase of pulmonary vascular resistance leading to right ventricular failure and premature death (Figure 1). Its prevalence ranges from 15 to 50 patients per million population and it affects a relatively young patient population (average age of 50 years) when compared with the more co...

Background Anomalous left coronary artery from the pulmonary artery (ALCAPA) is a rare congenital cardiovascular defect that occurs in approximately 1/300 000 live births or 0.5% of children with congenital heart disease. There are two types of ALCAPA syndrome: the infant type and the adult type. The most infants experience myocardial infarction and congestive heart failure, and approximately 9...

conclusions the fev1/fev6 ratio can be used as a valid surrogate for fev1/fvc in the diagnosis of airway obstruction, especially for screening purposes in high-risk populations for copd. moreover, fev6 is an acceptable alternative for fvc in detection of restrictive pattern. results this study shows that the current cut-off points used to detect obstruction and restriction can be replaced by fe...