the vehicle routing problem with simultaneous pickup and delivery (vrpspd) is a well-known combinatorial optimization problem which addresses provided service to a set of customers using a homogeneous fleet of capacitated vehicles. the objective is to minimize the distance traveled. the vrpspd is an np-hard combinatorial optimization problem. therefore, practical large-scale instances of vrpspd...

introduction: the number of systematic reviews and meta-analyses published in iran has increased significantly in recent years. writing these articles based on internationally accepted guidelines is one of the most important factors effective on their structural quality. this study aimed to assess the abstract of iranian systematic reviews and meta-analyses indexed in scopus. methods: this stud...

conclusions our meta-analysis, while not ruling out possible publication bias, showed no association between gene polymorphisms of apoc3 and the risk of nafld development in different populations in the world. evidence acquisition we performed a meta-analysis of all relevant studies published in the literature. a total of 115 clinical trials or reports were identified, but only seven trials met...

in this study, a bi-objective model for integrated planning of production-distribution in a multi-level supply chain network with multiple product types and multi time periods is presented. the supply chain network including manufacturers, distribution centers, retailers and final customers is proposed. the proposed model minimizes the total supply chain costs and transforming time of products ...

Multi-objective capacitated multiple allocation hub location problem (MOCMAHLP) is a variation of classic problem, which deals with network design, considering both the number and hubs connections between spokes, as well routing flow on network. In this study, we offer two meta-heuristic approaches based non-dominated sorting genetic algorithm (NSGA-II) archived multi-objective simulated anneal...

Meta-heuristics are algorithms which are applied to solve problems when conventional algorithms can not find good solutions in reasonable time; evolutionary algorithms are perhaps the most well-known examples of meta-heuristics. As there are many possible meta-heuristics, finding the most suitable meta-heuristic for a given problem is not a trivial task. In order to make this choice, one can de...

Optimization of machining parameters is a vital task for increasing machining efficiency and economics. Selection of optimal machining parameters is often performed by integrating empirical models with traditional mathematical and meta-heuristic algorithms. Ability to deal with complex and multi-dimensional optimization problems resulted in growing interest on the application of meta-heuristic ...