The spread of herpes simplex virus (HSV) was studied in the mouse central nervous system (CNS) after ocular inoculation. Sites of active viral replication in the CNS were identified by autoradiographic localization of neuronal uptake of tritiated thymidine. Labeled neurons were first noted in the CNS at 4 days postinoculation in the Edinger-Westphal nucleus, ipsilateral spinal trigeminal nucleu...

BACKGROUND The nucleus raphe magnus (NRM) is involved in thermoregulatory processing. There is a correlation between changes in the firing rates of the cells in the NRM and the application of the peripheral thermal stimulus. INTRODUCTION we examined the effect of reversible inactivation and excitation of NRM on mechanisms involved in tail blood flow (TBF) regulation in hypothermia. METHODS ...

The present study was designed to provide a detailed and quantitative description of the physiological characteristics of neurons in the medullary raphe magnus (RM) and adjacent nucleus reticularis magnocellularis (NRMC) under anesthetized conditions. The background discharge and noxious stimulus-evoked responses of RM and NRMC neurons were recorded in rats lightly anesthetized with isoflurane....

Migraine is one of the commonest neurological disorders. Despite intensive research, its exact pathomechanism is still not fully understood and effective therapy is not always available. One of the key molecules involved in migraine is glutamate, whose receptors are found on the first-, second- and third-order trigeminal neurones and are also present in the migraine generators, including the do...

There is evidence that serotonin [5-hydroxytryptamine (5-HT)] is involved in the physiological responses to hypercapnia. Serotonergic neurons represent the major cell type (comprising 15-20% of the neurons) in raphe magnus nucleus (RMg), which is a medullary raphe nucleus. In the present study, we tested the hypothesis 1) that RMg plays a role in the ventilatory and thermal responses to hyperca...

seems to be original. This goes to show that the human foetus exhibits signs of animation parallel with those of bodily configuration. In significance and purpose Albertus' observation is, therefore, far removed from Harvey's ideas, although the method is the same. It is not unlikely that Harvey was familiar with Albertus' text in which comparative embryology was treated on a broad Aristotelian...

This report describes a study project done at the Rudolf Magnus Institute (RMI) in the eld of neural network development. The goal of this study is to develop a neural network that is able to automatically classify rat behaviour from video. This project was started because of the great di erences in perception and classi cation of rat behaviour between human observers. Chapter 1 consists of a g...

We investigate the e¤ect of employee heterogeneity on the incentive to put forth e¤ort in a market-based tournament. Employers use the tournament’s outcome to estimate employees’ abilities and accordingly condition their wage o¤ers. Employees put forth e¤ort, because by doing so they increase the probability of outperforming the rival, thereby increasing their ability assessment and thus the wa...

Are fairness concerns of relevance to environmental economics and, if so, are they sufficiently structured to improve analysis in this field? On both of these questions, we answer in the affirmative, arguing that people’s fairness views are based on both general rules and the context, where context refers to the set of variables and persons employed to interpret and apply the principles. The fa...