نتایج جستجو برای: nrm

تعداد نتایج: 456  

2018
Francesco Saraceni Myriam Labopin Rose-Marie Hamladji Ghulam Mufti Gerard Socié Avichai Shimoni Jeremy Delage Eric Deconinck Patrice Chevallier Didier Blaise Jaime Sanz Anne Huynh Edouard Forcade Bipin N. Savani Mohamad Mohty Arnon Nagler

Background A preparatory regimen consisting of thiotepa-busulfan-fludarabine (TBF) has been associated with reduced relapse in patients with haematological malignancies after haploidentical and cord blood transplants; however, few data exist regarding TBF conditioning in sibling (MSD) and unrelated donor (URD) transplants for AML. Results Among patients receiving a myeloablative (MAC) regimen...

Journal: :Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2016
Christopher Groombridge Cheau Wern Chin Bernard Hanrahan Anna Holdgate

OBJECTIVES Preoxygenation prior to intubation aims to increase the duration of safe apnea by causing denitrogenation of the functional residual capacity, replacing this volume with a reservoir of oxygen. In the operating room (OR) the criterion standard for preoxygenation is an anesthetic circuit and well-fitting face mask, which provide a high fractional inspired oxygen concentration (FiO2 ). ...

Journal: :IEEE Transactions on Magnetics 2021

This article presents a comprehensive comparative study between two nonlinear solvers for the hybrid analytical modeling (HAM) formulation. The Newton-Raphson method (NRM) and fixed-point (FPM) are compared in terms of their convergence rate, computational time, accuracy. A new HAM formulation using loop-based magnetic equivalent circuit (MEC) instead node-based one is proposed to improve condi...

Journal: :The American Journal of the Medical Sciences 2021

Background Liberal oxygen therapy might increase the mortality rate of patients. Non-rebreathing masks (NRM) are a high-flow, non-invasive device that can provide concentration up to 95%. This study aimed determine impact using NRM in patients with respiratory failure. Methods retrospective cohort was conducted four medical institutions Taiwan from January 2010 December 2016. The association be...

Journal: :Journal of modern applied statistical methods : JMASM 2016
Rhonda D Szczesniak Dan Li Raouf S Amin

Semiparametric mixed models are increasingly popular for statistical analysis of medical device studies in which long sequences of repeated measurements are recorded. Monitoring these sequences at different periods over time on the same individual, such as before and after an intervention, results in nested repeated measures (NRM). Covariance models to account for NRM and simultaneously address...

Journal: :Blood 2011
David A Jacobsohn Mukta Arora John P Klein Anna Hassebroek Mary E Flowers Corey S Cutler Alvaro Urbano-Ispizua Brian J Bolwell Joseph H Antin Michael Boyiadzis Jean-Yves Cahn Mitchell S Cairo Roger H Herzig Luis M Isola Thomas R Klumpp Stephanie J Lee Effie W Petersdorf Stella Santarone Robert P Gale Harry C Schouten Stephen R Spellman Daniel J Weisdorf John R Wingard Mary M Horowitz Steven Z Pavletic

There is a paucity of information regarding the factors that affect nonrelapse mortality (NRM) and overall survival among children that develop chronic graft-versus-host disease (cGVHD). We performed multivariate analyses using data from the Center for International Blood and Marrow Transplant Research to identify risk factors for NRM and survival in 1117 pediatric subjects with leukemia or mye...

2016
Frédéric Baron Annalisa Ruggeri Eric Beohou Myriam Labopin Guillermo Sanz Noel Milpied Mauricette Michallet Andrea Bacigalupo Didier Blaise Jorge Sierra Gérard Socié Jan J. Cornelissen Christoph Schmid Sebastian Giebel Norbert-Claude Gorin Jordi Esteve Fabio Ciceri Bipin N. Savani Mohamad Mohty Eliane Gluckman Arnon Nagler

Nonrelapse mortality (NRM) is the first cause of treatment failure after unrelated cord blood transplantation (UCBT) following myeloablative conditioning (MAC). In the last decade, reduced-intensity conditioning (RIC) regimens have been developed with the aim of reducing NRM and allowing older patients and those with medical comorbidities to benefit from UCBT. The aim of the current retrospecti...

Journal: :Blood 2006
Wendy M Leisenring Paul J Martin Effie W Petersdorf Anne E Regan Nada Aboulhosn Jean M Stern Saundra N Aker Raymond C Salazar George B McDonald

Algorithms for grading acute graft-versus-host disease (GVHD) are inaccurate in assessing mortality risk. We developed a method to predict mortality by using data from 386 patients with acute GVHD. From the onset of GVHD to day 100, GVHD manifestations were scored for the skin, liver, and upper and lower gastrointestinal tract, and data were recorded for immunosuppressive treatment, performance...

2014
Jens M Chemnitz Geothy Chakupurakal Maya Bäßler Udo Holtick Sebastian Theurich Alexander Shimabukuro-Vornhagen Silke Leitzke Michael S Von Bergwelt-Baildon Christof Scheid

The introduction of reduced-intensity conditioning regimens has allowed elderly patients with preexisting comorbidities access to the potentially curative allogeneic stem cell transplantation. Patient's comorbidities at the time of treatment consideration play a significant role in transplant outcome in terms of both overall survival (OS) and nonrelapse mortality (NRM). The hematopoietic stem c...

2006
Dong Hwan Kim Sang Kyun Sohn Jin Ho Baek Jong Gwang Kim Nan Young Lee Dong Il Won Jang Soo Suh Kyu Bo Lee

Thrombocytopenia (TP) is a frequent complication after allogeneic stem cell transplantation (SCT) and regarded as a poor prognostic factor, especially in patients with chronic graft-versus-host disease (GVHD), although various factors were related to the development of TP after allogeneic SCT. Sixty-three patients receiving allogeneic peripheral blood stem cell transplantation (PBSCT) were stra...

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