The development of a biotechnological method for the production of new biologically active phosphatidylcholine containing monoterpene citronellic acid (CA) was the aim of this work. Incorporation of citronellic acid (CA) into egg-yolk phosphatidylcholine (PC) in the lipase-catalyzed acidolysis process was studied. Isoprenoid acid CA was used as an acyl donor and five commercially available immo...

An optimal continuous production of biodiesel by methanolysis of soybean oil in a packed-bed reactor was developed using immobilized lipase (Novozym 435) as a catalyst in a tert-butanol solvent system. Response surface methodology (RSM) and Box-Behnken design were employed to evaluate the effects of reaction temperature, flow rate, and substrate molar ratio on the molar conversion of biodiesel....

A panel of lipases was screened for the selective acetylation and alcoholysis of silychristin and silychristin peracetate, respectively. Acetylation at primary alcoholic group (C-22) of silychristin was accomplished by lipase PS (Pseudomonas cepacia) immobilized on diatomite using vinyl acetate as an acetyl donor, whereas selective deacetylation of 22-O-acetyl silychristin was accomplished by N...

enantio-3-Hydroxyambrox derivatives were obtained through combined chemical and microbiological methods from ent-12-o×o-13-epi-manoyl oxides. Regioselcctive and stereoselcctive reduction ofthe ¢~bonyl group at C-3 of ent-3,12-dioxo-13-epi-manoyl oxide was card ed out with Baker "s yeast. Regioselcctive acetyl ation of ent-3,12-dihydxoxy-13-epi-manoyl oxide was accomplished with Candida cylindra...

Here, we focused on a simple enzymatic epoxidation of alkenes using lipase and phenylacetic acid. The immobilised Candida antarctica lipase B, Novozym 435 was used to catalyse the formation of peroxy acid instantly from hydrogen peroxide (H2O2) and phenylacetic acid. The peroxy phenylacetic acid generated was then utilised directly for in situ oxidation of alkenes. A variety of alkenes were oxi...

The aim of this study was the evaluation two different procedures for one-pot transformation oil extracted from Citrus limon seeds to a mixture fatty acid methyl esters (FAMEs) and glycerol derivatives application as potential biofuel. Lemon seed obtained by Soxhlet extraction. first procedure realized efficient irreversible transesterification in hexane lipase B Candida antarctica (Novozym 435...

The esterification of rac-ibuprofen and rac-ketoprofen with glycerol catalyzed the commercial biocatalyst Novozym® 435 was investigated at 45 °C various profen: molar ratios using 2-propanol as co-solvent in a batch type reaction. conversion reached 46%, an enantiomeric excess towards S-enantiomer 42%. When 1:4 ibuprofen:glycerol ratio assayed, 75% R-ibuprofen reacted monoglyceride 99% selectiv...

Dynamic kinetic resolution (DKR) is one of the most attractive methods for enantioselective synthesis. In reported studies, lipase B from Candida antarctica (CALB) immobilized on siliceous mesoporous cellular foams (MCF) functionalized with different hydrophobic groups, and two ruthenium complexes substituted cyclopentadienyl ligands were investigated as catalysts chemoenzymatic DKR (rac)-1-phe...