The use of novel intercalating dyes as labels in DNA restriction fragment analysis by capillary electrophoresis with frequency-domain fluorescence lifetime detection is described. The dyes, including one mono-intercalating dye with three positive charges and three bis-intercalating, homodimeric dyes with four positive charges, were excited by the 488 nm line of an argon ion laser and exhibited ...

A series of cellulose ampholytes (CAms), with substitution degrees of cationic groups (DSC) of 0.41, 0.79, and 1.08, and with a substitution degree of anionic groups of 0.68, was prepared from sodium carboxymethylcellulose by a cationization reaction with 2,3-epoxypropyltrimethylammonium chloride. The obtained CAms were crosslinked by ethyleneglycoldiglycidylether (EGDE) to obtain cellulose pol...

The synthesis of eight novel squarylium cyanine dyes is described. The dyes exhibit high solubility in organic solvents due to the introduction of the 1-sulfonatopropyl group onto the N-atom of the indolenine moiety. The condensation of the indolenine with squaric acid preceded smoothly, the reaction being catalyzed by a weak base. Spectral parameters of the dyes were correlated with the nature...

Heptamethine cyanines are favorable for fluorescence imaging applications in biological systems owing to their near-infrared (NIR) absorption and emission. However, it is very difficult to quench the fluorescence of NIR dyes by the classic photoinduced electron transfer mechanism due to their relatively high-lying occupied molecular orbital energy levels. Herein, we present a simple and effecti...

Novel asymmetric monomeric monomethine cyanine dyes 5a-d, which are analogues of the commercial dsDNA fluorescence binder thiazole orange (TO), have been synthesized. The synthesis was achieved by using a simple, efficient and environmetally benign synthetic procedure to obtain these cationic dyes in good to excellent yields. Interactions of the new derivatives of TO with dsDNA have been invest...

135 ABSTRACT: Heavy metals and dyes are major contributors in contamination of water streams. These contaminants enter into our ecosystem, thus posing a significant threat to public health, ecological equilibrium and environment. Thus a combined discharge of these contaminants results in water pollution with high chemical oxygen demand, biological oxygen demand, color, particulate matter, suspe...

A series of novel bistriphenylamine-based organic sensitizers (coded as RC-dyes) with high molar extinction coefficients (.5.0 6 10 M cm) have been synthesized for dye-sensitized solar cells (DSSCs). By changing the length of the p-conjugation bridge thiophene from zero to two between the donor and the acceptor part, the range of absorption and its corresponding photon-to-current conversion was...

BACKGROUND Endoscopy capable of fluorescence observation provides histological information on gastrointestinal lesions. We explored the novel application of low pH-dependent fluorescent dyes for fluorescence observation of crypt structure and inflammatory cell infiltration in the colon. METHODS Low pH-dependent fluorescent dyes were applied to the colonic mucosa of normal mice for observation...

The cyanine dyes Cy3 and Cy5 have proven valuable in numerous applications involving conjugation with proteins. Practical syntheses of lysine-selective, succinimidyl ester derivatives of these dyes have been published, and succinimidyl esters are commercially available. However, the published syntheses of cysteine-selective derivatives produce relatively low yields from expensive starting mater...

We report on the synthesis, and photovoltaic performances of four novel Ru(ii)-bipyridine heteroleptic complexes TT206-209, incorporating branched and bulkier alkyl chains compared to their linear analogues C106 and CYC-B11 previously reported. In both series, we found that dyes containing 2-methyl-hex-2-yl substitution gave better performances than 1,1-dipropylbutyl. The best overall performan...