Notch signaling has been implicated in the pathogenesis of Kaposi sarcoma. Kaposi sarcoma is an angioproliferative neoplasm that originates fromKaposi sarcoma–associated herpesvirus (KSHV) infection. Previously, we showed that the KSHV LANA protein can stabilize intracellular Notch in KSHV-infected tumor cells and promote cell proliferation. However, whether Notch signaling functions in patholo...

A three-dimensional failure initiation criterion in brittle materials containing a sharp V-notch is presented and validated by experiments. It is based on simultaneous fulfilment of the stress requirement and a finite fracture mechanics energy release rate (ERR) requirement. Since the ERR cannot determine failure initiation direction for dominant mode III loading, the failure initiation orienta...

Notch signaling has been implicated in the pathogenesis of Kaposi sarcoma. Kaposi sarcoma is an angioproliferative neoplasm that originates from Kaposi sarcoma-associated herpesvirus (KSHV) infection. Previously, we showed that the KSHV LANA protein can stabilize intracellular Notch in KSHV-infected tumor cells and promote cell proliferation. However, whether Notch signaling functions in pathol...

Endotracheal tube (ETT) should be placed at the optimal level to avoid single lung ventilation or accidental extubation. This study was performed to estimate the mid-tracheal level by using surface anatomical landmarks in adult patients.Neck computed tomography images of 329 adult patients between the ages of 16 and 79 years were reviewed. In the midline sagittal plane, the levels corresponding...

Evaluation of the morphology of the suprascapular notch region is important from a clinical point of view because it is the most common site of suprascapular nerve compression and injury. A group of 120 patients underwent ultrasound examination of the suprascapular notch region according to our original four-stage "step-by-step" protocol. The notches were classified based on their morphology an...

The stator structure is one of the main factors affecting electromagnetic performance permanent magnet (PM) motors. In this paper, an in-depth study and analysis how to reduce cogging torque carried out from perspective structure. According theory synthesis, paper presents a unified calculation formula for different PM motor skewed notch designs. This verified with 20-pole, 60-slot 24-slot moto...

To the best of our knowledge, proposed for the first time is the design of an optically broadband variable photonic delay line (VPDL) using an electronically controlled variable focus lens (ECVFL), mirror motion, and beam-conditioned free-space laser beam propagation. This loss-minimized fiber-coupled VPDL design using micro-optic components has the ability to simultaneously provide optical att...

Aims and objectives: To evaluate the maxillary and mandibular morphology in different vertical facial types and to implicate the achieved results into diagnosis and treatment planning of patients requiring orthodontic treatment. Materials and methods: The present study is conducted on a sample of 120 subjects comprising of 60 males and 60 females in the age range of 18 to 25 years. The lateral ...