Background: Gold nanoparticles (GNPs) are among the most promising radiosensitive materials in radiotherapy. Studying the effective sensitizing factors such as nanoparticle size, concentration, surface features, radiation energy and cell type can help to optimize the effect and possible clinical application of GNPs in radiation therapy. In this study, the radiation sensitive polymer gel was use...

Self-oscillating polymer gel has become a distinguished class of smart soft materials. Here we fabricated and demonstrated a self-oscillating structural gel network with the incorporation of the Belousov-Zhabotinsky (BZ) reaction. The structural polymer gel oscillates at a macroscopic level with remarkably faster kinetics compared to a normal gel of similar chemical compositions. The structural...

Polymer gels are regarded as a potential dosimeter for independent validation of absorbed doses in clinical radiotherapy. Several imaging modalities have been used to convert radiation-induced polymerization to absorbed doses from a macro-scale viewpoint. This study developed a novel dose conversion mechanism by texture analysis of scanning electron microscopy (SEM) images. The modified N-isopr...

introduction: in radiotherapy, methods of treatment planning are becoming increasingly more complicated. this requires verification of the doses delivered to increasingly smaller and more precise regions. radiotherapy techniques are continuously employing smaller and smaller field sizes to deliver tighter radiation doses with higher therapeutic ratios, generating interest among researchers to p...

Since the introduction of volumetric chemical dosimetry with Fricke gel dosimeters in the 1980s, three-dimensional (3D) dosimetry has been a promising technique for the clinic, since it provides a unique methodology for 3D dose measurement of the complex conformal dose distributions achieved by modern techniques such as Intensity Modulated and Volumetric Arc Radiation Therapy. In the last decad...

background: the human body contains of different tissues and cavities with different physical and radiological properties. most important among these are tissues and cavities that are radiologically different from water, including lungs, sinuses and bones. gel dosimetry provides a unique feature to display dose distributions occurring in clinical radiation therapy in three dimensions. materials...

Introduction: Bismuth-based nanoparticles having high atomic number and electron density, besides of being utilized as CT contrast agent, stand as a strongly proposed method for dose enhancement in radiotherapy. Embedded nanoparticle in polymer gel dosimeter poses the first step to assess the dose enhancement capability in nanoparticles. To this end, MAGICA gel dosimeter, whic...

The use of polymer gels to record radiation dose distributions in three dimensions was first proposed in 1992 as a proof-of-principle [1]. The accuracy of these early polymer gel dosimeters and scanning methods was not sufficient for most clinical applications [2]. Since then, several efforts were made to increase the accuracy and precision of both the physical gel dosimeter and the scanning te...