A 70-year-old man was being evaluated for back pain. Two years earlier he was found to have a monoclonal IgA protein (0.3 g/dL). Past history included long-standing history of ulcerative colitis with a partial colectomy and ileostomy 31 years earlier. A magnetic resonance imaging scan showed numerous destructive vertebral lesions. His complete blood count was normal except for a minimal normocy...

Pearson marrow‑pancreas syndrome (PS) is a progressive multi‑organ disorder caused by deletions and duplications of mitochondrial DNA (mtDNA). PS is often fatal in infancy, and the majority of patients with PS succumb to the disease before reaching three‑years‑of‑age, due to septicemia, metabolic acidosis or hepatocellular insufficiency. The present report describes the case of a four‑month‑old...

Introduction: Lung cancer could have signs and symptoms generated by paraneoplastic syndromes. This study aimed to describe analyze hematologic syndrome in patients with lung Indonesia. Methods: was a cross-sectional analytic conducted Persahabatan National Respiratory Referral Hospital, Jakarta, between September 2018 February 2019, on all newly diagnosed whose diagnosis established who fulfil...

BACKGROUND: The introduction of erythropoietin has transformed the management of anaemia in CKD, with considerable benefits which includes enhanced quality of life, increased exercise capacity and improved cardiac function. There is paucity of data on the beneficial effects of this treatment from this environment. OBJECTIVE: The aim of this work was to study the pattern and response of anaemia ...

BACKGROUND Anaplasma ovis infections can cause clinical symptoms in acute phase and lead to huge economic losses in flocks. The aim of the present study was to investigate the hematological and parasitological changes in experimental anaplasmosis in sheep with Iranian strain of A. ovis. METHOD Five male sheep without any blood parasite infection were selected. One hundred ml heparinized blood...

Myelophthisis is a form of bone marrow failure due to the substitution of hematopoietic tissue and its stroma by abnormal tissue. We report a case of a 38-year-old woman under investigation for bicytopenia during maintenance chemotherapy (tamoxifen) for breast cancer (diagnosed 3 years previously). Her physical examination was unremarkable except for pallor. There was no hepatosplenomegaly, lym...

BACKGROUND Anemia is the most common hematological abnormalities in HIV patients and it is a wide spread public health problem. The World Health Organization estimates that over 2 billion people are anemic worldwide with more than 100 million of these anemic children living in Africa. In Ethiopia, there is limited information about the prevalence and factors associated with anemia among HIV pos...

A 20-year-old nonverbal patient with profound developmental disabilities was treated with intravenous piperacillin-tazobactam for respiratory infection. After 8 days, he became afebrile with normal pulmonary status, but his pulse remained inexplicably rapid (114/minute). Investigations revealed severe normochromic normocytic hemolytic anemia (hemoglobin: 40 g/L, reticulocytes: 9.4%, nucleated e...

In mammals, the production of red blood cells is tightly regulated by the growth factor erythropoietin (EPO). Mice lacking a functional Epo gene are embryonic lethal, and studying erythropoiesis in EPO-deficient adult animals has therefore been limited. In order to obtain a preclinical model for an EPO-deficient anemia, we developed a mouse in which Epo can be silenced by Cre recombinase. After...