OBJECTIVE To determine eosinophil and mast cell populations in gastric and duodenal mucosal biopsies of adults with nonulcer dyspepsia (NUD) as compared to non-dyspeptic adults. STUDY DESIGN A case control study. PLACE AND DURATION OF STUDY Shahid Sadoughi University of Medical Sciences, Yazd, Iran, from January 2010 to June 2011. METHODOLOGY A total of 52 (25 non-ulcer dyspeptic patients...

Functional dyspepsia in children is classified as a subset of functional pediatric gastrointestinal disorders. According to ROME II criteria, it is divided into 3 groups including ulcer-like dyspepsia, dysmotility-like dyspepsia and unspecified (non-specific) dyspepsia. Prevalence of functional dyspepsia had been reported around 3/5 of children and adolescents who presented with clinical dyspep...

The aim of the study was to determine the frequency of functional and organic dyspepsia and possible predictors for organic dyspepsia in coronary artery disease (CAD) patients. The 150 patients (109 men; mean age 62.61 +/- 10.23 yr) undergoing coronary artery by-pass grafting because of stable pectoral angina due to significant CAD were enrolled in the study. Dyspepsia was determined by the exi...

Introduction Dyspepsia is a common gastrointestinal diseases worldwide with a prevalence ranging from 7 to 40%. Dyspepsia, more commonly known as heartburn or indigestion, is defined as one or more of the following symptoms: postprandial fullness, early satiation (the inability to finish a normal size meal), or epigastric pain or burning for at least 3 months in the past year. Dyspepsia has bee...

PURPOSE Interstitial cystitis (IC) is one of the most bothersome conditions in urological practice. There are 2 subtypes, classic and nonulcer IC, with similar symptoms but different outcomes with respect to clinical course and response to treatment. Histologically there are fundamental differences between the 2 subtypes, classic IC presenting a severe abnormality of the urothelium and characte...

Dyspepsia is a common problem that is important from the perspectives of both patient health and economics. While there has been variability in the definitions used to describe dyspepsia, there have also been few standardized outcomes tools designed to measure dyspepsia-related health, especially in relation to changes in dyspepsia over time. An evaluative tool was developed, the Severity of Dy...

AIMS To investigate interleukin (IL)-12 (p40) and IL-10 mRNA expression levels in the gastric mucosa in relation to H pylori cag status, peptic ulceration, and histopathology. METHODS In 81 dyspeptic patients, antral and corpus biopsies were taken for reverse transcriptase polymerase chain reaction (RT-PCR) and histology. G3PDH (control) and IL-10 and IL-12 were coamplified in a duplex PCR an...

diary cards for severity of dyspeptic symptoms in patients with non-ulcer dyspepsia. Eur J Surg 1998;164(suppl 583):106-11. 10 Jaeschke R, Singer J, Guyatt GH. Measurement of health status. Ascertaining the minimal clinically important difference. Controlled Clin Trials 1989;10:407-15. 11 Wiklund IK, Junghard O, Grace E, Talley NJ, Kamm M, Veldhuyzen van Zanten SJO, et al. Quality of life in re...

OBJECTIVE To estimate the prevalence of dyspepsia in the general population aged over 20 in western Iran. METHODS The cross-sectional study was conducted among the randomly selected general population over the age of 20 years in Sanandaj city. Iran, from April to December 2009. A questionnaire containing demographic, symptoms and history variables was used. Dependent variables were self-repor...

BACKGROUND Many risk factors have been speculated to be associated with uninvestigated dyspepsia amongst different population groups. Some of which have been subjected to epidemiological survey while others remain unevaluated. OBJECTIVE We evaluated some of the documented risk factors amongst patient presenting with uninvestigated dyspepsia and compared with a matched group without dyspepsia ...