The present study was designed to fabricate a new chitosan-collagen sponge (CCS) for potential wound dressing applications. CCS fabricated by 3.0% chitosan mixture with 1.0% type I collagen (7:3(w/w)) through freeze-drying. Then the prepared evaluate its properties series of tests. new-made demonstrated safety toward NIH3T3 cells. Furthermore, showed significant surround inhibition zone than em...

Cytotoxicity tests of zinc sulfide (ZnS) and cadmium sulfide (CdS) quantum dots (QDs) synthesized via all-aqueous process with various surface conditions were carried out with human endothelial cells (EA hy926) using two independent viability assays, i.e., by cell counting following Trypan blue staining and by measuring Alamar Blue (AB) fluorescence. The ZnS QDs with all four distinct types of ...

Bacillus thuringiensis crystal (Cry) proteins are the most widely used biological insecticides in the world. Their value in safely controlling insects that destroy crops and transmit human diseases is well established.Here, we reviewB. thuringiensisCry proteins as novel anthelmintics with a unique mode of action. In laboratory studies, Cry proteins are highly effective against a broad range of ...

As a new category of therapeutics for skin diseases including atopic dermatitis (AD), nucleic acids are gaining importance in the clinical setting. Intradermal administration is noninvasive and improves patients' quality of life. However, intradermal small interfering RNA (siRNA) delivery is difficult because of two barriers encountered in the skin: intercellular lipids in the stratum corneum a...

DC-SIGN is a dendritic cell-specific C-type lectin receptor that recognizes highly glycosylated ligands expressed on the surface of various pathogens. This receptor plays an important role in the early stages of many viral infections, including HIV, which makes it an interesting therapeutic target. Glycomimetic compounds are good drug candidates for DC-SIGN inhibition due to their high solubili...

Nowadays available by clean industrial processes, dimethyl carbonate (DMC) possesses properties of nontoxicity and biodegradability which make it a true green reagent/solvent to devise syntheses that prevent pollution at the source. In particular, the versatile reactivity of DMC allows both methylation and carboxymethylation protocols that can replace conventional and highly noxious reagents su...

BACKGROUND Recent researches have been focusing on mucosal immune adjuvants, which play the key roles in mucosal immunization and have become the limitation for non-injected vaccine development. Escherichia coli heat-labile enterotoxin B subunit (LTB) was regarded as a promising mucosal adjuvant for its nontoxicity and potent activity. LTB preparation issues have always been recurring, in part ...

Antrodia camphorata (AC), a precious and unique folkloric medicinal mushroom enriched in polyphenolics, isoflavonoids, triterpenoids, and polysaccharides, has been diversely used in Formosa (Taiwan) since the 18th century. In this study, prostate cancer (PCa) cell lines PC-3 (androgen independent) and LNCaP (androgen responsive) were treated with AC crude extract (ACCE) at 50-200 microg/mL, res...

The Diels–Alder reaction is a powerful tool in organic synthesis and in the chemical industry. Recently an increased attention has been focused on the development of green methods for the purpose of improving rate and selectivity of this reaction. In recent years, ionic liquids (ILs) have gained a lot of attention as green solvents in organic synthesis and other chemical processes. This is main...

Recently, regulatory dendritic cells (DCregs), a newly described dendritic cell subset with potent immunomodulatory function, have attracted increased attention for their utility in treating immune response-related diseases, such as graft-versus-host disease, hypersensitivity, and autoimmune diseases. Danchaiheji (DCHJ) is a traditional Chinese formula that has been used for many years in the c...