Polyamines have been associated with a large number of plant growth and developmental processes. In particular, they have been associated with floral initiation with increased polyamines concentration occurring during flowering in horticulture plants. However, there is limited information about polyamines in cotton (Gossypium hirsutum L.) and how they are distributed in the cotton plant. In add...

BACKGROUND Prone whole breast irradiation (WBI) leads to reduced heart and lung doses in breast cancer patients receiving adjuvant radiotherapy. In this feasibility trial, we investigated the prone position for whole breast + lymph node irradiation (WB + LNI). METHODS A new support device was developed for optimal target coverage, on which patients are positioned in a position resembling a ph...

Introduction: Developmental changes in atrioventricular nodal conduction time and refractoriness have been shown in several studies. Prevalence of atrioventricular nodal reentrant tachycardia (AVNRT) is clearly age-dependent. The purpose of this study was to determine developmental changes of basic and frequency-dependent electrophysiological properties of the atrioventricular node (AV-node)...

Cripto-1, a co-receptor for Nodal, can activate Nodal-dependent and Nodal-independent signaling pathways. In this study we have investigated whether Cripto-1 mutants, that fail to activate a Nodal-dependent signaling pathway, are capable to activate a Nodal-independent signaling pathway in mammary epithelial cells. Cripto-1 mutants expressed in EpH4 mouse mammary epithelial cells are fully func...

Nodal, an important embryonic morphogen, has been reported to modulate tumorigenesis. Epithelial-mesenchymal transition (EMT) plays an important role in cancer metastasis. We have previously reported that recombinant Nodal treatment can promote melanoma undergoing EMT, but the effects of endogenous Nodal on EMT are still unknown. Here we generated both Nodal-overexpression and -knockdown stable...

introduction: the aim of the present study was to determine direct effects of no modulation on protective electrophysiological properties of atrioventricular node (av node) in the experimental model of af in rabbit. methods: isolated perfused rabbit av nodal preparations were used in two groups. in the first group (n=7), lname (50μm) was applied. in the second group (n=12), different concentrat...

The paper deals with a technique of sensitivity calculation in linear hybrid networks containing elements with both lumped and distributed parameters when the multiconductor transmission lines (MTL) are considered as the distributed parts. The technique utilizes the modified nodal analysis (MNA) method to do overall description of the network enabling determining sensitivities with respect to b...

Recently proposed methods for ordering sparse symmetric matrices are discussed and their performance is compared with that of the Minimum Degree and the Minimum Local Fill algorithms. It is shown that these methods applied to symmetrized modified nodal analysis matrices yield orderings significantly better than those obtained from the Minimum Degree and Minimum Local Fill algorithms, in some ca...

The Transforming Growth Factor-ß (TGFß) family ligand Nodal is an essential embryonic morphogen that is associated with progression of breast and other cancers. It has therefore been suggested that Nodal inhibitors could be used to treat breast cancers where Nodal plays a defined role. As secreted antagonists, such as Cerberus, tightly regulate Nodal signaling during embryonic development, we u...