نتایج جستجو برای: nmo fmri

تعداد نتایج: 37154  

2009
Brian G Weinshenker

Neuromyelitis optica (NMO) can be distinguished from MS by clinical, radiological and serological findings, especially the tendency for spinal cord lesions to be longer than 3 vertebral segments during acute attacks and the presence of aquaporin-4 autoantibodies in NMO. The spectrum of NMO is broader than previously realized and includes recurrent myelitis, recurrent optic neuritis, certain cer...

2013
Felix Schmidt Önder Göktas Sven Jarius Brigitte Wildemann Klemens Ruprecht Friedemann Paul Lutz Harms

Background. Neuromyelitis optica (NMO) is a severely disabling autoimmune disorder of the CNS, which mainly affects the optic nerves and spinal cord. However, recent studies have shown that extra-opticospinal are more common in NMO than previously thought. Objective. To investigate olfactory function (OF) in patients with neuromyelitis optica (NMO) versus healthy controls (HC). Methods. Psychop...

2015
Esther Melamed Michael Levy Patrick J. Waters Douglas Kazutoshi Sato Jeffrey L. Bennett Gareth R. John Douglas C. Hooper Albert Saiz Amit Bar-Or Ho Jin Kim Lakha Pandit Maria Isabel Leite Nasrin Asgari Najib Kissani Rogier Hintzen Romain Marignier Sven Jarius John Marcelletti Terry J. Smith Michael R. Yeaman May H. Han Orhan Aktas Metha Apiwattanakul Brenda Banwell Denis Bichuetti Simon Broadley Philippe Cabre Tanuja Chitnis Jerome De Seze Kazuo Fujihara Benjamin Greenberg Kerstin Hellwig Raffaele Iorio Eric Klawiter Ingo Kleiter Marco Lana-Peixoto Nakashima Kevin O'Connor Jacqueline Palace Friedman Paul Naraporn Prayoonwiwat Klemens Ruprecht Olaf Stuve Thomas Tedder Silvia Tenembaum Juan P. Garrahan Buenos Aires Katja van Herle Danielle van Pelt Pablo Villoslada Emmanuelle Waubant Brian Weinshenker Dean Wingerchuk Jens Würfel Scott Zamvil

Neuromyelitis optica (NMO) (and NMO spectrum disorder) is an autoimmune inflammatory disease of the CNS primarily affecting spinal cord and optic nerves. Reliable and sensitive biomarkers for onset, relapse, and progression in NMO are urgently needed because of the heterogeneous clinical presentation, severity of neurologic disability following relapses, and variability of therapeutic response....

Journal: :Neurology 2016
Silvia Tenembaum Tanuja Chitnis Ichiro Nakashima Nicolas Collongues Andrew McKeon Michael Levy Kevin Rostasy

Neuromyelitis optica (NMO) is a severe autoimmune disease of the CNS characterized by recurrent inflammatory events primarily involving the optic nerves and spinal cord. NMO is infrequent in children, but early recognition is important to start adequate treatment. In this article, we review the evolving diagnostic criteria of NMO and provide an update on the clinical and neuroimaging spectrum o...

2016
Chen Cheng Ying Jiang Xiaodong Lu Fu Gu Zhuang Kang Yongqiang Dai Zhengqi Lu Xueqiang Hu

BACKGROUND Acute brainstem syndrome (ABS) may herald multiple sclerosis (MS), neuromyelitis optica (NMO), or occur as an isolated syndrome. The aquaporin 4 (AQP4)-specific serum autoantibody, NMO-IgG, is a biomarker for NMO. However, the role of anti-AQP4 antibody in the conversion of ABS to NMO is unclear. METHODS Thirty-one patients with first-event ABS were divided into two groups accordin...

Journal: :Middle East Fertility Society Journal 2021

Abstract Background Estradiol is an important marker of ovarian response to stimulation in ART cycles. The study tries find the correlation serum estradiol on day HCG trigger number follicles, oocytes retrieved, and mature oocytes, also, correlate per follicle oocyte HCG, oocytes. It a cross sectional using retrospective data. Results data 232 patients were analyzed. Our showed positive between...

2013
Doralina Guimarães Brum Marcelo Rizzatti Luizon Antônio Carlos Santos Marco Aurélio Lana-Peixoto Cristiane Franklin Rocha Maria Lucia Brito Enedina Maria Lobato de Oliveira Denis Bernardi Bichuetti Alberto Alan Gabbai Denise Sisterolli Diniz Damacio Ramon Kaimen-Maciel Elizabeth Regina Comini-Frota Claudia E. Vieira Wiezel Yara Costa Netto Muniz Roberta Martins da Silva Costa Celso Teixeira Mendes-Junior Eduardo Antônio Donadi Amilton Antunes Barreira Aguinaldo Luiz Simões

BACKGROUND Neuromyelitis optica (NMO) is considered relatively more common in non-Whites, whereas multiple sclerosis (MS) presents a high prevalence rate, particularly in Whites from Western countries populations. However, no study has used ancestry informative markers (AIMs) to estimate the genetic ancestry contribution to NMO patients. METHODS Twelve AIMs were selected based on the large al...

2016
Michalina Jasiak-Zatonska Alicja Kalinowska-Lyszczarz Slawomir Michalak Wojciech Kozubski

Neuromyelitis optica (NMO) is an autoimmune, demyelinating disorder of the central nervous system (CNS) with typical clinical manifestations of optic neuritis and acute transverse myelitis attacks. Previously believed to be a variant of multiple sclerosis (MS), it is now considered an independent disorder which needs to be differentiated from MS. The discovery of autoantibodies against aquapori...

Journal: :Archives of neurology 2009
Andrew McKeon James P Fryer Metha Apiwattanakul Vanda A Lennon Shannon R Hinson Thomas J Kryzer Claudia F Lucchinetti Brian G Weinshenker Dean M Wingerchuk Elizabeth A Shuster Sean J Pittock

OBJECTIVE To compare the sensitivity and specificity of immunofluorescence (IF) and immunoprecipitation (IP) assays using green fluorescent protein-tagged aquaporin-4 (AQP4) in 6335 patients for whom serological evaluation was requested on a service basis. DESIGN Case-control study. SETTING Mayo Clinic Neuroimmunology Laboratory (Rochester, Minnesota) and Departments of Neurology (Rochester...

2012
Frederic Blanc Vincent Noblet Barbara Jung François Rousseau Felix Renard Bertrand Bourre Nadine Longato Nadjette Cremel Laure Di Bitonto Catherine Kleitz Nicolas Collongues Jack Foucher Stephane Kremer Jean-Paul Armspach Jerome de Seze

Neuromyelitis optica (NMO) is an inflammatory disease of central nervous system characterized by optic neuritis and longitudinally extensive acute transverse myelitis. NMO patients have cognitive dysfunctions but other clinical symptoms of brain origin are rare. In the present study, we aimed to investigate cognitive functions and brain volume in NMO. The study population consisted of 28 patien...

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