With over 34 000 new cases and ~12 400 deaths from multiple myeloma (MM) anticipated in 2021 the United States1 about twice as many Europe, there is an unmet medical need for therapies patients with previously treated MM that have progressed on available agents. Currently, are few agents mechanisms of action approved early-line treatment. Selinexor (XPOVIO, Karyopharm Therapeutics Inc.) a poten...

Financial/Actuarial Mathematics Wednesday, August 26, 2015, 3:00pm-4:00pm 1360 East Hall Katsumasa Nishide (Yokohama National University) Heston-Type Stochastic Volatility with a Markov Switching Regime We construct a Heston-type stochastic volatility model with a Markov switching regime to price a plain-vanilla stock option. A semi-analytic solution, which contains a matrix ODE is obtained and...