نتایج جستجو برای: nitazoxanide

تعداد نتایج: 375  

Journal: :The Indian Journal of Pediatrics 2019

Journal: :JPMA. The Journal of the Pakistan Medical Association 2014
Sajjad Ali Sunil Mumar Kiran Kalam Kapeel Raja Shehla Baqi

OBJECTIVE To document the prevalence, clinical presentation and treatment outcome of cryptosporidiosis in immunocompetent adult patients presenting with acute diarrhoea. METHODS This prospective cohort study was conducted at the Sindh Institute of Urology and Transplantation Karachi from February 1, till September 30, 2012. All immunocompetent adult patients who presented with acute diarrhoea...

2010
Laura V. Ashton Robert L. Callan Sangeeta Rao Gabriele A. Landolt

Infection of dogs with canine influenza virus (CIV) is considered widespread throughout the United States following the first isolation of CIV in 2004. While vaccination against influenza A infection is a common and important practice for disease control, antiviral therapy can serve as a valuable adjunct in controlling the impact of the disease. In this study, we examined the antiviral activity...

Journal: :Current tropical medicine reports 2015
Hayley Sparks Gayatri Nair Alejandro Castellanos-Gonzalez A Clinton White

Cryptosporidiosis is increasingly recognized as an important global health concern. While initially reported in immunocompromised such as AIDS patients, cryptosporidiosis has now been documented as a major cause of childhood diarrhea and an important factor in childhood malnutrition. Currently, nitazoxanide is the only proven anti-parasitic treatment for Cryptosporidium infections. However, it ...

Journal: :The Journal of Infection in Developing Countries 2020

Journal: :Antimicrobial agents and chemotherapy 2012
N Nagata D Marriott J Harkness J T Ellis D Stark

Dientamoeba fragilis is a commonly encountered trichomonad which has been implicated as a cause of gastrointestinal disease in humans. Despite the frequency of reports recording infections with this parasite, little research has been undertaken in terms of antimicrobial susceptibility. The aim of this study was to evaluate the susceptibility of D. fragilis to several commonly used antiparasitic...

2016
Andrés Palencia Ru-Juan Liu Maria Lukarska Jiri Gut Alexandre Bougdour Bastien Touquet En-Duo Wang Xianfeng Li M. R. K. Alley Yvonne R. Freund Philip J. Rosenthal Mohamed-Ali Hakimi Stephen Cusack

The apicomplexan parasites Cryptosporidium and Toxoplasma are serious threats to human health. Cryptosporidiosis is a severe diarrheal disease in malnourished children and immunocompromised individuals, with the only FDA-approved drug treatment currently being nitazoxanide. The existing therapies for toxoplasmosis, an important pathology in immunocompromised individuals and pregnant women, also...

Journal: :Journal of virology 2013
Simone La Frazia Alessandra Ciucci Francesca Arnoldi Maurizio Coira Patrizia Gianferretti Mara Angelini Giuseppe Belardo Oscar R Burrone Jean-Francois Rossignol M Gabriella Santoro

Rotaviruses, nonenveloped viruses presenting a distinctive triple-layered particle architecture enclosing a segmented double-stranded RNA genome, exhibit a unique morphogenetic pathway requiring the formation of cytoplasmic inclusion bodies called viroplasms in a process involving the nonstructural viral proteins NSP5 and NSP2. In these structures the concerted packaging and replication of the ...

2016
Diana F Florescu Uriel Sandkovsky

Diarrhea is a common complication in solid organ transplant (SOT) recipients and may be attributed to immunosuppressive drugs or infectious organisms such as bacteria, viruses or parasites. Cryptosporidium usually causes self-limited diarrhea in immunocompetent hosts. Although it is estimated that cryptosporidium is involved in about 12% of cases of infectious diarrhea in developing countries a...

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