Objective: Black cumin (Nigella sativa L.) seeds and its crude extract or essential oils have been widely used traditionally for nutritional medicinal applications in Asian countries. Its effects on diabetics with high fat diet consumption not adequately studied. This study was undertaken to body weight, abdominal girth, lipid profile plasma glucose levels diabetic fed rats. Materials Methods :...

Seasonal allergic rhinitis (SAR) is one of the top reasons for patient visits to primary care physicians because of its bothersome symptoms. This highly prevalent disease also impairs quality of life, sleep, and work. Oral antihistamines are one of the most frequently prescribed medications for the management of SAR but they have their own side effects. Hence the effects of traditional Nigella ...

Hexane extract of the seeds of Nigella sativa L. prevented pregnancy in Sprague-Dawley rats treated orally at 2 g/kg daily dose on days 1-10 post-coitum. Significant antifertility activity was also observed in its column fractions and subfractions. At contraceptive dose, the active hexane extract exhibited only mild uterotrophic activity comparable almost to 0.002 mg/kg dose of 17 varies; is di...

Background Thymoquinone is one of the active ingredients of black cumin (Nigella sativa L.) essential oil possessing antiinflammatory, antineoplastic, neuroand hepatoprotective properties. Some of these properties were attributed to an antioxidant activity of thymoquinone, which seems to be unlikely from its structure. Because the lipophilic thymoquinone exhibits a structural similarity with th...

Aims: In various studies and also in traditional medicine, many properties for Nigella sativa, such as antioxidant effects and gastric mucosa protection have been reported. The aim of this study was to investigate the effect of hydro-alcoholic extract of Nigella sativa on acid and mucus secretion in cyclooxygenase inhibition conditions. Materials & Methods: This interventional study was done us...