n 1559, Jean Nicot, a French ambassador in Lisbon, sailed o Portugal to negotiate the marriage of Princess Marguerite e Valois to King Sebastian of Portugal. When he returned, e brought tobacco plants which had an immediate success, nd was called nicotine: the term later came to refer only to he active ingredient of the plant, which was identified as an lkaloid. Nicotine is a major component of...

BACKGROUND This study assessed the correlation between nicotine dependence and salivary cotinine levels in tobacco chewers and checked the reliability of Fagerstorm test in tobacco cessation programmes. METHODS The study sample included 75 tobacco chewers aged between 20 to 50 years. Self-reported nicotine dependence was evaluated using Fagerstorm Test for Nicotine dependence-smokeless tobacc...

introduction: the influence of ascorbic acid on the nicotine-induced conditioned place preference (cpp) and behavioral sensitization was investigated in the present study. methods: in a pilot study, place conditioning and locomotor activity were investigated after nicotine (0.25, 0.5, 0.75, 1, 1.5 and 2 mg/kg) or ascorbic acid (1, 10, 100 and 1000 mg/kg) administration. different doses of ascor...

nicotine transdermal systems are being used as an aid to smoking cessation programs. as the kinetics of nicotine delivery is important in success of a smoking cessation program, rapid and high input of nicotine is required, which is not possible by passive methods and requires enhancement strategies such as iontophoresis. iontophoretic permeation, of nicotine looks promising, based on published...

conclusions the prevalence of nicotine use among ferdowsi university students is lower than the prevalence in the general population of iran and the prevalence in other countries. results for cigarette use, 17.6% of respondents reported using cigarettes at least once, 3.7% reported using cigarettes occasionally, and 3.9% reported using cigarettes on a regular basis. for water-pipe use, the corr...

objective(s): present study was performed in order to uncover new aspects for nicotine-induced damages on spermatogenesis cell lineage. materials and methods: for this purpose, 36 mature male wistar rats were divided into three groups as; control-sham (0.2 ml, saline normal, ip), low dose (0.2 mg/kg bw-1, ip) nicotine-received and high dose (0.4 mg/kg bw-1, ip) nicotine-received groups. followi...

There is concern about the potentially increasing use of tobacco in Angola. However, information on the frequency and determinants of this use is not systematised. This study aimed to estimate the prevalence of tobacco consumption and nicotine dependence among smokers in an Angolan population and considering individual socio-demographic and behavioural characteristics. A community-based survey ...

OBJECTIVE To estimate the prevalence of female sexual dysfunction symptoms and the associated risk factors in a sample of patients with substance-related disorders admitted to a specialized in-patient care unit. METHODS This study used a cross-section design, with eight months of data collection, conducted with substance-dependent women using structured questionnaires to collect socio-demogra...

OBJECTIVES To investigate whether age is associated with access to smoking cessation services. DESIGN Data from the Smoking Toolkit Study 2006-2015, a repeated multiwave cross-sectional household survey (n=181 157). SETTING England. PARTICIPANTS Past-year smokers who participated in any of the 102 waves stratified into age groups. OUTCOME MEASURES Amount smoked and nicotine dependency, ...