Sener, Alp, and Francine G. Smith. Glomerular and tubular responses to NG-nitro-L-arginine methyl ester are age dependent in conscious lambs. Am J Physiol Regulatory Integrative Comp Physiol 282: R1512–R1520, 2002; 10.1152/ ajpregu.00628.2001.—The present experiments were carried out to investigate the role of endogenously produced NO in modulating renal function during postnatal maturation und...

A role for nitric oxide (NO) in the regulation of blood leukocyte numbers was examined in BALB/c mice by employing the NO synthase inhibitor NG-nitro L-arginine methyl ester (L-NAME). Treatment of animals with a single dose of 50 mg/kg body wt caused a dramatic increase in the number of circulating neutrophils and a moderate decrease in the number of circulating lymphocytes. These effects were ...

  Urinary N-acetyl-β-D-glucosalninidase (NAG) has been proved to be a useful marker of early renal injury as a result of factors such as lead toxicity. In this study the effect of lead acetate on the kidney and its correlation with the nitric oxide (NO) system was investigated by determining the NAG release in perfused kidney of rat. Lead acetate caused a time- and dose-dependent increase in en...

Abstract Arsenic (As) negatively affects plant development. This study evaluates how the application of silicon (Si) can favor formation adventitious roots in rice under arsenate stress (AsV) as a mechanism to mitigate its negative effects. The simultaneous AsV and Si up-regulated expression genes involved nitric oxide (NO) metabolism, cell cycle progression, auxin (IAA, indole-3-acetic acid) b...