background: microglial cells act as the sentinel of the central nervous system .they are involved in neuroprotection but are highly implicated in neurodegeneration of the aging brain. when over-activated, microglia release pro-inflammatory factors, such as nitric oxide (no) and cytokines, which are critical in eliciting neuroinflammatory responses associated with neurodegenerative diseases. thi...

Esse estudo investiga o risco de crédito com duplicatas no Brasil. Usamos dados proprietários uma central registros recebíveis que permitem a consulta informações sobre documento fiscal das transações comerciais junto às Secretarias Fazenda estaduais. Analisamos 129 mil notas fiscais eletrônicas (NF-e) 3.459 empresas, realizaram operações 240 agentes financeiros, valor total R$633 milhões. 10 t...

Background and Aim: Neurofibromatosis-1(NF-1) is a common genetic condition in children. It is becoming increasingly recognized that in neurofibromatosis, there might be anomalous development of bone with or without any local anomaly of neuro-ectodermal basis. This review was conducted to highlight the different features of spinal disorders in this congenital disease. Methods and Materials: Di...

Background: The death of neurons and cerebral edema are the main consequences of stroke. However, inflammatory processes play a key role in aggravating cerebral damage following stroke. The aim of this study was to investigate the effects of Viola odorant extract (VOE) on infarct volume (IV), neurologic deficits (ND), and expression of NF-κB and VCAM-1 in the MCAO model. Method: The animals we...

This study provides new data on chromosomal characteristics and DNA barcoding of three endemic loaches of Iran: spiny southern loach Cobitis linea (Heckel, 1847), Persian stream loach Oxynoemacheilus persa (Heckel, 1848) and Tongiorgi stream loach Oxynoemacheilus tongiorgii (Nalbant & Bianco, 1998). The chromosomes of these fishes were investigated by examining metaphase chromosome spreads obta...

Achieving high−efficiency and stable hydrogen evolution from water splitting is a great challenge. Herein, facilely prepared two−dimenssional self−supported catalytic electrode with excellent stability constructed for large−scale production alkaline simulated seawater. The bifunctional by fast mild one−step of sodium borohydride etching on nickel foam (NF) substrate without adding other additiv...