reaction of glycin with malononitrile afforded respective pyrrole. pyrrole is one of the heterocyclic compounds with very important biological activities. heterocycles are extremely important because of their wide range of applications that goes from their use as pharmaceuticals and agrochemicals to dyestuffs and additives. in this view, it was proposed to synthesize pyrrole-3-carbonitrile deri...

financial derivatives are new instruments through which hedging, investment and arbitrage are done in a modern economy. although the word 'derivative'primarily reminds us of options and futures, the major focus of the equity derivatives industry worldwide is on index derivatives. launching index options and index futures in tehran stock exchange, not only increases financial market de...

Background:The spread of drug-resistant microbial strains has led many studies for identifying, designing, and synthesizing new antimicrobial agents.The aim of this study was to evaluate antimicrobial effects of some synthesized potassium dithiocarbazinate derivatives against 6 Gram-negative and 4 Gram-positive bacteria as well as 2 molds and 1 yeast. Potassium salts of dithiocarbazinic acids w...

objective(s):according to the prevalence of neoplastic diseases, there is a deep necessity for discovery of novel anticancer drugs in the field of medicinal chemistry. in the current study, a new series ofphenylthiazole derivatives(compounds 4a-4f) was synthesizedand theiranticancer activity was assessed in vitro. materials and methods:all synthesized derivatives were evaluated towards three hu...

Various antibacterial fluoroquinolone compounds were prepared by the direct amination of 7-halo-6- fluoroquinolone-3-carboxylic acids with a variety of piperazine derivatives and (4aR,7aR)-octahydro-1H-pyrrolo[3,4-b] pyridine using Zirconia Sulfuric Acid (ZrSA) nanoparticle, as a catalyst in the presence of ordinary or magnetized water upon reflux condition. The results showed that ZrSA exh...