نتایج جستجو برای: neuroprotectant
تعداد نتایج: 379 فیلتر نتایج به سال:
BACKGROUND The efficacy of hypothermia as a neuroprotectant has yet to be demonstrated in acute ischemic stroke. We conducted a phase I pilot study to assess the feasibility and safety of performing intravascular hypothermia after definitive intra-arterial reperfusion therapy (IAT). METHODS ReCCLAIM (Reperfusion and Cooling in Cerebral Acute Ischemia) is a prospective single-arm open-label cl...
Effective interventions that provide obvious neuroprotection are currently fairly limited. Glucagon-like peptide-1 (GLP-1), an enhancer of insulin production with a trophic effect on β cells in the islets, has been found to be trophic for neuronal cells. Alogliptin benzoate (AGL), a selective inhibitor of dipeptidylpeptidase-4 (DPP-4) functioning as a long-acting agonist of GLP-1, is in clinica...
Centella asiatica (L.) has many active ingredients with important roles, including as antioxidant, anti-inflamation and neuroprotectant. can reduce inflammatory reactions by inhibiting the activity of TNF-α. Thus, is a potential alternative therapy for traumatic brain injury reducing inflammation via TNF-α expression modulation. This study aimed to determine effect on serum levels in rat model ...
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