Peripheral neuropathy is underappreciated as a potential cause of functional limitations. In the present article, we assessed the cross-sectional association between peripheral neuropathy and physical functioning and how the longitudinal association between age and functioning differed by neuropathy status. Physical functioning was measured in 1996–2008 using timed performances on stair-climb, ...

introduction: ischaemic-reperfusion nerve injury has been suggested as the mechanism for post-tourniquet limb paralysis. as dexamethasone (dex) has been shown to prevent ischaemic-reperfusion process in some tissues, we tested the hypothesis that this drug would reduce tourniquet induced nerve injury. methods: 36 male wistar rats (200-250 gr) were chosen and divided randomly into 6 equal groups...

Background: Diabetes, low nighttime blood pressure, and nonarteritic ischemic optic neuropathy may be associated. Not too many studies present whether this relationship applies to patients. Objective: Diabetes mellitus, pressure at night, were studied in a group of individuals. Methods: The ophthalmology clinic will conduct cross-sectional research on patients with from March 2019 December 2021...

To report a case of anterior ischemic optic neuropathy (AION) following COVID-19 vaccination and provide systematic review all published cases vaccination. A literature search was performed using PubMed Ovid MEDLINE for Terms used in the included “COVID-19 vaccination”, “optic neuropathy”, neuritis”, “ischemic neuropathy”. Titles abstracts were initially screened then full texts eligible studie...

A 24 years old man with known history of asthma came acute presentation ascending weakness for4 days following flu like symptoms and worsening asthma. His complete blood counts showed elevated eosinophil count. Nerve conduction neuropathy. Diagnosed Churg Strauss syndrome due to presence asthma, eosinophilia, neuropathy pulmonary infiltrates. is systemic eosinophilic vasculitis involving multip...

objective(s):painful diabetic neuropathy is associated with hyperexcitability and hyperactivity of spinal cord neurons. however, its underlying pathophysiological mechanisms have not been fully clarified. induction of excitatory/inhibitory neurotransmission imbalance at the spinal cord seems to account for the abnormal neuronal activity in diabetes. protective properties of neurosteroids have b...

background and aims: charcot marie tooth disease (cmt) is the most prevalent hereditary neuropathy and its frequency is 1 in 2500. cmt is a heterogeneous disease and has different clinical symptoms. the prevalence of cmt and involved genes differ in different countries. cmt patients experience considerable sleep problems and a higher risk of decreased quality of life. in this work it was aimed ...

introduction hypoparathyroidism might cause various musculoskeletal findings, resembling spondyloarthropathies. case presentation we described a 52-year-old woman, diagnosed as a case of undifferentiated spondyloarthropathy for ten years, who was unresponsive to classic anti-inflammatory therapies. she developed anterior ischemic optic neuropathy and had elevated muscle enzymes during the cours...

abstract background: diabetic neuropathy is the most common micro-vascular complications of diabetes. the drugs including gabapentin and duloxetine are often used for the treatment of pain associated with diabetic neuropathy. this study aimed to compare the efficacy of duloxetine and gabapentin in the treatment of diabetic peripheral neuropathy. materials and methods: totally, 34 patients aged ...