نتایج جستجو برای: neurooncology
تعداد نتایج: 163 فیلتر نتایج به سال:
This article addresses the issue of preoperative planning in the surgical treatment of brain pathologies in the light of current concepts of the functional organization of the human brain. The primary issues discussed here include general neurosurgical strategy, modern diagnostic techniques (including function al magnetic resonance, tractography, and cortical sti mu la tion), image guided surge...
1 Research Group Genome Organization & Function, German Cancer Research Center (DKFZ) & BioQuant, 69120 Heidelberg, Germany 2 Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, 07747 Jena, and Research Group Network Modelling, Leibniz Institute for Natural Product Research and Infection Biology Hans Knöll Institute (HKI), 07745 Jena, G...
Neuroanatomy has entered a new era, culminating in the search for the connectome, otherwise known as the brain's wiring diagram. While this approach has led to landmark discoveries in neuroscience, potential neurosurgical applications and collaborations have been lagging. In this article, the authors describe the ideas and concepts behind the connectome and its analysis with graph theory. Follo...
Whole-genome sequencing studies have recently identified a quarter of cases of the rare childhood brainstem tumor diffuse intrinsic pontine glioma to harbor somatic mutations in ACVR1. This gene encodes the type I bone morphogenic protein receptor ALK2, with the residues affected identical to those that, when mutated in the germline, give rise to the congenital malformation syndrome fibrodyspla...
Although radionecrosis has been exhaustively described in depth in the neurooncological literature, its diagnosis is still a challenging issue because its radiological pattern is frequently indistinguishable from that of tumor recurrence. This review discusses the causes of radionecrosis and the potential effect of adjuvant chemotherapy concomitant with radiotherapy on its rate and onset. The p...
The diagnosis of brain glioma can challenging, particularly when the masses are very large. While the majority of gliomas are astrocytomas or oligodendrogliomas, enough are of other types that awareness of these others is critical. This course will begin with a review of some of the distinctive features of common and less common brain tumours, with particular focus on the distinctions that make...
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