نتایج جستجو برای: neurodevelopment
تعداد نتایج: 3448 فیلتر نتایج به سال:
Integrating evidence from multiple domains is useful in prioritizing disease candidate genes for subsequent testing. We ranked all known human genes (n=3819) under linkage peaks in the Irish Study of High-Density Schizophrenia Families using three different evidence domains: 1) a meta-analysis of microarray gene expression results using the Stanley Brain collection, 2) a schizophrenia protein-p...
BACKGROUND Intra-amniotic inflammation is associated with adverse pregnancy and neonatal outcomes. However, the impact on child neurodevelopment remains unclear. We aim to assess the effect of intra-amniotic inflammation on neurodevelopmental outcomes in children. METHODS The databases MEDLINE, Embase, CINAHL, and Cochrane will be searched from their inception until November 2017. Randomized ...
BACKGROUND AND OBJECTIVE Infants and young children in low to middle-income countries are at risk for adverse neurodevelopment due to multiple risk factors. In this study, we sought to identify stimulation and learning opportunities, growth, and burden of respiratory infections and diarrhea as predictors for neurodevelopment. METHODS We visited 422 North Indian children 6 to 30 months old wee...
BACKGROUND Lead (Pb) adversely affects neurodevelopment in children. Neural stem cells (NSCs) play an essential role in shaping the developing brain, yet little is known about how Pb perturbs NSC functions and whether such perturbation contributes to impaired neurodevelopment. OBJECTIVES We aimed to identify Pb-induced transcriptomic changes in NSCs and to link these changes to neurodevelopme...
OBJECTIVES We evaluated whether neighborhood characteristics correlated with early neurodevelopment and whether these characteristics confounded the previously reported association between exposure to chlorpyrifos (an organophosphate insecticide) and neurodevelopment. METHODS We obtained prenatal addresses, chlorpyrifos exposure data, and 36-month Psychomotor Development Index (PDI) and Menta...
Hypoxic Ischemic Encephalopathy (HIE) score may be used to predict neurodevelopment outcome in infants with birth asphyxia. A total of 140 infants who had a 5 min Apgar score of <7 at birth had detailed motor and neurodevelopment assessment. Outcome measures were grouped as normal or abnormal with morbidity (convulsions, abnormal muscle tone and delayed development) or death. The positive predi...
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