Stem cell research has obtained much prominence in recent years for its therapeutic potential in dealing with serious diseases, many of which are essentially incurable by routine therapies. Mesenchymal stem cells with pluripotency and immunomodulatory properties are suitable candidates for tissue engineering and regenerative medicine. Today, nanofibrous scaffolds are widely used in tissue en...

Abstract Purpose Peripheral nerve injury (PNI) and its regeneration continue to remain a significant medical burden worldwide. The current treatment strategies used treat PNI are often associated with multiple complications yet do not achieve complete motor sensory functions. Recently, synthetic biodegradable conduits have become one the most commonly repair small gaps in injury. But they shown...

Organ dysfunction is a major cause of morbidity and mortality. Transplantation typically the only definitive cure, challenged by lack sufficient donor organs. Tissue engineering encompasses development biomaterial scaffolds to support cell attachment, proliferation, differentiation, leading tissue regeneration. For efficient clinical translation, forming technology utilized must be suitable for...

currently autografts are gold standards for craniomaxillofacial bone regeneration. but autografts have some limitations. bone tissue engineering has been introduced to overcome these limitations. it consist three components: stem cells, growth factor, and scaffold. scaffold provides an environment for bone growth and simplifies cell adhesion, differentiation and proliferation. in this review, a...

in this paper, the focus is on a new kind of biodegradable semi-interpenetrating polymer networks, which derived from ɛ-caprolactone, lactide, 1,4-butane diisocyanate and ethylenediamine and also its potential has been investigated in soft tissue engineering applications. the polymers were characterized by nuclear magnetic resonance (nmr) spectrometry, fourier transform infrared spectroscopy (f...

tissue engineering based on the adipose derived stem cells  promote a strong strategy to propagation of bone, cartilage and fat tissues in the three-dimensional scaffolds, fabricated by combining biological materials with suitable and appropriate growth factors.  in this study, a peo scaffold was used to show that mesenchymal stem cells can attach well; the aim of this study was the investigati...

in this investigation, hydroxyapatite (hap) nanostructure with uniform morphologies, controllable size, nano-dispersion and narrow-size distribution in diameter has been synthesized successfully by low-temperature hydrothermal process, and the as-synthesized powders were characterized by energy-dispersive x-ray spectroscopy, scanning electron microscopy, high-resolution transmission electron mi...