STUDY DESIGN In vivo strain techniques were used in an animal radiculopathy model. OBJECTIVE To quantify the severity of compressive nerve root injury and characterize its effect on resultant mechanical allodynia in a lumbar radiculopathy model. SUMMARY OF BACKGROUND DATA Clinical and experimental work indicate many factors contributing to radicular pain mechanisms, including mechanical inj...

during the past few years, researchers and practitioners have developed novel techniques, using ansa cervicalis to innervate muscles of the larynx paralyzed due to surgical procedures carried out in the chest and neck areas. during routine dissection of a middle-age male cadaver, an unusual course of the superior root of the ansa cervicalis was observed. in this case, the superior root of the a...

Frontier-based exploration is the most common approach to exploration, a fundamental problem in robotics. In frontierbased exploration, robots explore by repeatedly detecting (and moving towards) frontiers, the segments which separate the known regions from those unknown. A frontier detection sub-process examines map and/or sensor readings to identify frontiers for exploration. However, most fr...

In this work, we extend a previously demonstrated entropy based groupwise registration method to include a free-form deformation model based on B-splines. We provide an efficient implementation using stochastic gradient descents in a multi-resolution setting. We demonstrate the method in application to a set of 50 MRI brain scans and compare the results to a pairwise approach using segmentation...

It has been recently discovered by Bell, Heinle and Levandovskyy that a large class of algebras, including the ubiquitous G-algebras, are finite factorization domains (FFD for short). Utilizing this result, we contribute an algorithm to find all distinct factorizations of a given element f ∈ G, where G is any G-algebra, with minor assumptions on the underlying field. Moreover, the property of b...

The sclera is the white outer shell and principal load-bearing tissue of the eye as it sustains the intraocular pressure. We have hypothesized that the mechanical properties of the posterior sclera play a significant role in and are altered by the development of glaucoma-an ocular disease manifested by structural damage to the optic nerve head. An anisotropic hyperelastic constitutive model is ...

“Molecular Cybernetics” is an emerging research field aiming the development of “Chemical AI”, artificial intelligence with memory and learning capabilities based on molecular communication. It originated from Robotics”, which studies systems that comprise three basic elements robots; Sensing, Planning, Acting. Development Amoeba-type robot (unicellular cell,) motivated construction multicellul...

PURPOSE Scleral stiffening has been proposed as a treatment for glaucoma to protect the lamina cribrosa (LC) from excessive intraocular pressure-induced deformation. Here we experimentally evaluated the effects of moderate stiffening of the peripapillary sclera on the deformation of the LC. METHODS An annular sponge, saturated with 1.25% glutaraldehyde, was applied to the external surface of ...

PURPOSE To characterize optic nerve head (ONH) connective tissue deformation after acute (15 or 30 minutes) intraocular pressure (IOP) elevation in six adult normal monkeys using three-dimensional (3-D) histomorphometry. METHODS Trephined ONH and peripapillary sclera from both eyes of six monkeys, each perfusion fixed with one eye at IOP 10 mm Hg (IOP-10) and the other at IOP 30 or 45 mm Hg (...

This study investigated the effects of wrist angle, sex, and handedness on the changes in the median nerve cross-sectional area (MNCSA) and median nerve diameters, namely longitudinal diameter (D1) and vertical diameter (D2). Ultrasound examination was conducted to examine the median nerve at the proximal carpal tunnel in both dominant and nondominant hands of men (n = 27) and women (n = 26). A...