Globally, over 1 000 000 new cases of neonatal tetanus occur annually. About 75% of these babies die, most of them in countries of the third world.' Data from Nigeria are largely hospital based, but case fatality rates currently are approximately 50%.23 However, in one community based study, the mortality rate was 11.9 per 1000 live births.4 In the University of Port Harcourt Teaching Hospital,...

OBJECTIVE To examine the relationship between antenatal care, iron and folic acid supplementation and tetanus toxoid vaccination during pregnancy in Indonesia and the risk of early neonatal death (death in days 0-6 of life). METHODS We analysed pooled data on neonatal survival in singleton infants born in the 5 years before each of the Indonesian demographic and health surveys of 1994, 1997 a...

introduction: tetanus is a serious infectious disease and the most common cause of neonatal mortality in developing countries. although neonatal tetanus (nt) can be prevented by immunization of expectant mothers, good hygiene and asepsis during delivery, total eradication of organism is not possible. methods: the cross-sectional study was done on 480 pregnant women after delivery. data was coll...

A total of 35 of the 59 countries that had not eliminated maternal and neonatal tetanus (MNT) as a public health problem in 1999 have since achieved the MNT-elimination goal. Neonatal tetanus deaths have decreased globally from 200,000 in 2000 to 49,000 in 2013. This is the result of increased immunization coverage with tetanus toxoid-containing vaccines among pregnant women, improved access to...

Background: Tetanus has remained a major public health problem worldwide although it is a vaccine preventable disease. It is a major contributor to under-five morbidity and mortality globally. Its effect is worse in developing countries such as Nigeria. Aims and Objectives: To highlight the socio-economic challenges in the management of Post neonatal tetanus at the University of Port Harcourt T...

Background Tetanus is an acute vaccine preventable illness manifested by neuromuscular dysfunction due to a potent exotoxin, tetanospasmin produced by Clostridium tetani. It is a common health problem in developing countries like Ethiopia. The aim of this study was to assess clinical profile and outcome of Pediatrics tetanus in a referral hospital, South Ethiopia. Methods This is a retrospect...

An estimated 400,000 deaths occur annually from neonatal tetanus (NT). In 1989 WHO adopted the goal of eliminating NT as a public health problem worldwide. To achieve this, and to control non-neonatal tetanus (non-NT), WHO recommends that newborns be passively protected at birth by the antepartum administration of at least two doses of tetanus toxoid (TT) to their mothers and that all children ...

60 infants with neonatal tetanus were treated at random either by 40 000 units of equine tetanus antitoxin (TAT), intravenously and intramuscularly, or by 40 000 units TAT, IV and IM, plus 150 units of human tetanus immune globulin TIG) intrathecally. There were 30 infants in each treatment group. Babies were similar in age, sex, weight, incubation period, temperature, and signs and symptoms on...

In a prospective study, 161 infants with neonatal tetanus were randomised to receive (a) standard treatment, or (b) standard treatment together with intrathecal equine antitetanus serum, or (c) intrathecal antitetanus serum with systemic betamethasone. There was no difference in survival between the three treatment groups in infants with severe tetanus, but in mild tetanus those who received st...