Excitotoxic cell death is the fundamental process responsible for many human neurodegenerative disorders, yet the basic mechanisms involved are not fully understood. Here, we exploited the fact that the immature brain is remarkably resistant to seizure-induced excitotoxic cell death and examined the underlying protective mechanisms. We found that, unlike in the adult, seizures do not increase t...

A continuous electronic fetal monitoring (efm) reduces the risk of neonatal seizure by 50% compared with intermittent auscultation (IA) (strength of recommendation [SOR]: A, systematic review of randomized controlled trials [RCTs]). EFM increases the incidence of cesarean section by 66% and the incidence of operative vaginal delivery by 16% (SOR: A, systematic review of RCTs). It has no effect ...

Seizures in newborn babies are commonly caused by problems such as lack of oxygen, haemorrhage, meningitis, infection and strokes. The aim of an automated neonatal seizure detection system is to assist clinical staff in a neonatal intensive care unit to interpret the EEG. In this work, the automated neonatal seizure detection system is validated on a set of healthy patients and its performance ...

Introduction: Neonatal Seizure is defined as a paroxysmal involuntary disturbance of cerebral function. seizures are common problem. Common etiology neonatal brain disorders, hypoxic-ischemic encephalopathy, central nervous system (CNS) infections, CNS bleeds, and structural anomalies the or secondary to metabolic problems, for example, hypoglycemia, hyponatremia, other electrolyte disturbances...

INTRODUCTION
 Neonatal seizure, a common problem encountered in neonatal intensive care unit (NICU) setting, is an important determinant of outcome neurological disorders newborn period. The aim the study was to clinical and etiological profile seizures along with their outcomes.
 MATERIAL AND METHODS
 A prospective observational conducted NICU Department Pediatrics at Universal C...

OBJECTIVE Neonatal seizures are the most common neurological symptoms and often signal an underlying serious neurologic condition. This study determines the frequency of neonatal seizure, predisposing factors, and brain computed tomography (CT) scan findings. MATERIALS & METHODS In a descriptive cross-sectional study, we evaluated all neonates with seizures who had been hospitalized in Besat ...

BACKGROUND The cerebral function monitor (CFM) is widely used to detect neonatal seizures, but there are very few studies comparing it with simultaneous electroencephalography (EEG). OBJECTIVE To determine the accuracy of non-expert use of the CFM and to assess interobserver agreement of CFM seizure detection. PATIENTS Babies admitted to the neonatal intensive care unit at King's College Ho...