OBJECTIVE To determine the factors associated with mortality in a hospitalised cohort of infants in Asmara, Eritrea. DESIGN Retrospective cross-sectional review of all 2006 admissions to a specialised neonatal intensive care unit. Data on gestational age (prematurity), age at presentation, birth weight, gender, mode of delivery, Apgar score, maternal age, birth location, admission diagnosis, ...

Data from four multicenter trials1-4 indicates that hypothermia is effective in diminishing brain injury in some neonates with moderate to severe hypoxic-ischemic encephalopathy (HIE). Currently, hypothermia is emerging as a standard of care for certain neonates with HIE. Meta-analysis suggests the therapy may prevent long-term neurologic deficits in one neonate for every 8 treated.5 Since hypo...

Gluckman, P., Wyatt, J. S., Azzopardi, D., Ballard, R., Edwards, A.D., Ferriero, D.M., Polin, R. A., Robertson, C., Thoresen, M., Whitelaw, A., Gunn, A. J. Selective Head Cooling With Mild Systemic Hypothermia After Neonatal Encephalopathy: Multicentre Randomized Trial Background: Cerebral hypothermia can improve outcome of experimental perinatal hypoxia-ischaemia. We did a multicenter randomis...

The aim of this study is to describe the experiences of becoming a parent to a child with birth asphyxia treated with hypothermia in the neonatal intensive care unit (NICU). In line with the medical advances, the survival of critically ill infants with increased risk of morbidity is increasing. Children who survive birth asphyxia are at a higher risk of functional impairments, cerebral palsy (C...

BACKGROUND Hypothermia initiated in the first six hours of life in term infants with hypoxic ischemic encephalopathy reduces the risk of death and severe neurological sequelae. Our study's principal objective was to evaluate transport predictors potentially influencing arrival in NICU (Neonatal Intensive Care Unit) at a temperature ≥35-<36°C. METHODOLOGY/PRINCIPAL FINDINGS A multi-centric, pr...

Therapeutic hypothermia (TH) is now considered a standard in tertiary NICUs. Amplitude-integrated electroencephalography (aEEG) is an important adjunct to this therapy and is gaining acceptance for use on the neonatal population. It can be easily incorporated into practice with appropriate education and training. Current publications are lacking regarding nursing care of neonatal patients under...

 Special Bed for neonate. Unfortunately in majority of setups proper warming system in neonatal/pediatric surgical units have not been available. This aspect of neonatal surgical care was discussed in the Neonatal Surgery research Group (NSRG) which is a discussion group on face book. Many learned members shared their experiences and advocated recommendations for optimal management and prevent...

Purpose: Extremely low birth weight (ELBW) infants exhibit immature thermoregulation and are easily exposed to hypothermia. We investigated the association between hypothermia on admission with short- long-term outcomes.Methods: Medical records of ELBW admitted neonatal intensive care unit a tertiary medical center June 2012 February 2017 were retrospectively analyzed. Upon admission, axillary ...

Perinatal asphyxia can result in neuronal injury with long-term neurological and behavioral consequences. Although hypothermia may provide some modest benefit, the intervention itself can produce adverse consequences. We have investigated whether xenon, an antagonist of the N-methyl-D-aspartate subtype of the glutamate receptor, can enhance the neuroprotection provided by mild hypothermia. Cult...