Despite the introduction of therapeutic hypothermia, neonatal hypoxic ischemic (HI) brain injury remains a common cause of developmental disability. Development of rational adjuvant therapies to hypothermia requires understanding of the pathways of cell death and survival modulated by HI. The conceptualization of the apoptosis-necrosis "continuum" in neonatal brain injury predicts mechanistic i...

ABSTRACT Objectives. The study aims to assess the trend of neonatal, post-neonatal, and infant mortality from 1996 2020 within metropolitan region state Rio de Janeiro other regions. Methods. Ecological using as analysis unity. Data were accessed Mortality Information System Live Birth in capital Janeiro, neighboring areas Niterói, São Gonçalo, Baixada Fluminense, remaining regions State. We ap...

background: hospital infections are a main cause of infant death among hospitalized infants in the neonatal wards. this research was conducted aiming to assess the medical staff's knowledge of hospital infections. methods: this is a cross-sectional study, conducted in all neonatal in isfahan hospitals wards. 65 nurses answerd to a questionnaire. results: results showed that 66.7% considered sep...

abstract background: in 1958, silverman demonstrated that maintenance ofbody temperature reduces mortality in low birth weight infants. from the early 1990s it was already recognized that adequate environmental warmth was essential in the case of newborns. however, neonatal hypothermia continues to be a significant issue in developing countries. methods: in order to describe the incidence and s...

OBJECTIVE This study aimed to assess the contribution of postnatal services to the risk of neonatal mortality, and the relative contributions of antenatal iron/folic acid supplements and postnatal care in preventing neonatal mortality in Indonesia. DESIGN Retrospective cohort study. SETTING AND PARTICIPANTS Data used in this study were the 2002-2007 Indonesia Demographic and Health Surveys,...

The atypical BH3-only protein Bcl-2/adenovirus E1B 19-kDa interacting protein 3 (BNIP3) is an important regulator of hypoxia-mediated cell death. Interestingly, the susceptibility to BNIP3-mediated cell death differs between cells. In this study we examined whether there are mechanistic differences in BNIP3-mediated cell death between neonatal and adult cardiac myocytes. We discovered that BNIP...

OBJECTIVE To introduce a fuzzy linguistic model for evaluating the risk of neonatal death. METHODS The study is based on the fuzziness of the variables newborn birth weight and gestational age at delivery. The inference used was Mamdani's method. Neonatologists were interviewed to estimate the risk of neonatal death under certain conditions and to allow comparing their opinions and the model ...

INTRODUCTION In low income and middle income countries, neonatal mortality remains high despite the gradual reduction in under five mortality. Newborn death contributes for about 38% of all under five deaths. This study has identified the magnitude and independent predictors of neonatal mortality in rural Ethiopia. METHODS This population based nested case control study was conducted in rural...

hypothermia is one of the main causes of neonatal mortality in developing countries. the aim of this prospective study was to determine the relationship between hypothermia at birth and the risk of mortality or morbidity among neonates born in imam hospital in tehran, iran. during a one-year period, body temperature was taken from all newborns using a low-reading rectal thermometer, immediately...