in NCC. Detailed analysis of one protease, the gelatinase MMP9, confirmed its distribution in cranial and trunk NCC. Exogenous MMP9 resulted in enhanced and precocious delamination of NCC, evident by Foxd3 or HNK1 staining. Conversely, prevention of MMP9 production or activation, using morpholino oligonucleotides or a pharmacological inhibitor, respectively, revealed a dramatic inhibition in NC...

choice. However, the data regarding the surgical management of NCC is quite insufficient, especially for extraparenchymal NCC. Many scholars advocate that anti-parasitic therapy should be considered as a priority in parenchymal NCC and steroids and anti-epileptic drugs are also chosen commonly in case of brain edema and seizures caused by the cysticerci (2,5,10). In contrast, extraparenchymal N...

Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system that affects thousands of people all over the world, mainly in Latin America (Mexico, Central America, equatorial zone, and Brazil), Asia (India and China), and Africa. Also because of the high immigration rates from endemic to nonendemic areas, NCC is now commonly seen in countries that were previously ...

the objective of this research was to compare the tensile, permeability, solubility and color properties of plasticized starch-polyvinyl alcohol-montmo-rillonite (ps-pva-mmt) and plasticized starch-polyvinyl alcohol-cellulose nanocrystal (ps-pva-ncc) bionanocomposite flms. the results showed that adding mmt (7%), increased the ultimate tensile strenght from 4.2 mpa to 4.61 mpa, however, ncc (7%...

Neuro-cysticercosis (NCC) and Japanese encephalitis (JE) are common in tropical countries. Two cases of NCC with coexistent JE are presented, which share same socio-demographic and ecologic factors and have the same intermediate host (pig). Patients were on treatment for NCC and presented in comatose state. Sudden clinical deterioration of a patient with NCC should warrant a search for coexiste...

The objective of this study was to analyze different immunoglobulins classes (IgG, IgM, IgE and IgA) against Cysticercus cellulosae in the cerebrospinal fluid (CSF), through enzyme linked immunosorbent assay (ELISA), correlating them to clinical and tomographic profiles in patients with neurocysticercosis (NCC). Eighty-five specimens of CSF were obtained from 43 cases with NCC (26 with the acti...

UNLABELLED Neurocysticercosis (NCC) is a common central nervous system infection caused by Taenia solium metacestodes. OBJECTIVE To investigate the occurrence of depression in patients with calcified NCC form. The study group consisted of 114 patients subdivided in four groups: NCC with epilepsy, NCC without epilepsy, epilepsy without NCC and chronic headache. METHOD Depression was evaluate...

To detect IgG antibodies to Taenia solium, a controlled double-blind study was conducted using 91 coded cerebrospinal fluid samples from patients with neurocysticercosis (NCC) and other neurologic disorders. Samples were tested in an enzyme-linked immunosorbent assay (ELISA) using metacestode excretion/secretion antigens. The results were correlated with data from medical records on the diagnos...

BACKGROUND Neurocysticercosis (NCC), the central nervous system infection by Taenia solium larvae, is a preventable and treatable cause of epilepsy. In Sub-Saharan Africa, the role of NCC in epilepsy differs geographically and, overall, is poorly defined. We aimed at contributing specific, first data for Rwanda, assessing factors associated with NCC, and evaluating a real-time PCR assay to diag...

Animal studies have shown that the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus can activate the thiazide-sensitive NaCl cotransporter (NCC). A common side effect of CNIs is hypertension. Renal salt transporters such as NCC are excreted in urinary extracellular vesicles (uEVs) after internalization into multivesicular bodies. Human studies indicate that CNIs also increase NCC abund...