Naturally occurring insecticides are abundant and varied in their effects, though but a few are articles of commerce. Even for these, pyrethrum, nicotine, rotenone, hellebore, ryania, and sabadilla, there is a paucity of information on mammalian toxicology and environmental effects. In general, these materials are characterized favorably by low acute toxicity and ready dissipation in nature. Un...

Asbestos causes progressive pulmonary fibrosis (asbestosis), pleural disease (eVusion and pleural plaques), and malignancies such as bronchogenic carcinoma and malignant mesothelioma. Asbestos is a generic term for a group of naturally occurring hydrated silicate fibres whose tensile strength and resilient structural and chemical properties are ideally suited for various construction and insula...

Asbestos causes progressive pulmonary fibrosis (asbestosis), pleural disease (eVusion and pleural plaques), and malignancies such as bronchogenic carcinoma and malignant mesothelioma. Asbestos is a generic term for a group of naturally occurring hydrated silicate fibres whose tensile strength and resilient structural and chemical properties are ideally suited for various construction and insula...

Human serum antibodies which react different pepsin-digested IgA proteins only with antigenic determinants rewas found in individual sera but no revealed by digestion of IgA with pepsin lationship to either IgA subgroups or were found in 29.2 per cent of the sera genetically determined IgA antigens was from 369 hospitalized patients studied. discerned. The presence of these antiThese antibodies...

This review, with 350 references, gives information on the chemical study of 234 naturally occurring tetraoxygenated xanthones in 12 families, 53 genus and 182 species of higher plants, and two which are described as fungal and lichen metabolites. The value of these groups of substances in connection with pharmacological activity and therapeutic use of some species is described. The structural ...

Lung carcinomas and pulmonary fibrosis (asbestosis) occur in asbestos workers. Understanding the pathogenesis of these diseases is complicated because of potential confounding factors, such as smoking, which is not a risk factor in mesothelioma. The modes of action (MOA) of various types of asbestos in the development of lung cancers, asbestosis, and mesotheliomas appear to be different. Moreov...

Asbestos associated diseases consist of both benign and malignant conditions. A rare constellation of asbestosis, laryngeal carcinoma, and malignant peritoneal mesothelioma occurring in a patient with long term occupational exposure to airborne asbestos fibres is presented. The observation illustrates the powerful disease-causing potential of occupational exposure to asbestos. A brief discussio...