The present document is a consensus statement reached by a panel of experts on noninvasive methods for assessment of airway inflammation in the investigation of occupational respiratory diseases, such as occupational rhinitis, occupational asthma, and nonasthmatic eosinophilic bronchitis. Both the upper and the lower airway inflammation have been reviewed and appraised reinforcing the concept o...

Chronic neurologic diseases are common sequelae of COVID. They severely impact the quality life and increase burden on healthcare systems. The long COVID neurological symptoms due to robust replication SARS-CoV-2 in nasal neuroepithelial cells, leading neuroinvasion, persistent infection, inflammation central nerve system (CNS).

An epidemiologic investigation on Staphylococcus aureus (S. aureus) colonization in atopic skin diseases ZDV FRQGXFWHG DW øQ|Q 8QLYHUVLW\ 7XUJXW g]DO 0HGLFDO &HQWHU 7KH LQFLGHQFH RI XQDIIHFWHG VNLQ OHVLRQDO skin, and nasal positivity for S. aureus was examined in a total of 60 patients with atopic dermatitis and other atopic skin diseases. 50 healthy subjects were studied as controls. Normal s...

Since nasal NK/T-cell lymphoma and NK/T-cell lymphoma nasal type are rare diseases, colonic involvement has seldom been seen. We report a case of a patient with a primary NK/T-cell lymphoma nasal type of the colon. The patient had no history of malignant diseases and was diagnosed after exhaustive study in the context of fever of unknown origin. The first therapeutic approach followed the DA-EP...

Background: Nasal polyps, a common clinical problem, are characterized by eosinophilic and mast cell inflammation.  The role of allergy and IgE in pathogenesis of nasal polyps is still unclear.  IgE receptors are important components of the immunological pathway in allergic and inflammatory diseases. Objective: To determine if the low affinity IgE receptor (CD23) is presented on nasal polyp tis...

In normal upper airways, nitric oxide is generated by the paranasal sinus epithelium and then diffuses into the nasal cavities. This study examined whether or not nasal NO concentration is affected by paranasal sinus inflammatory diseases. The influence of obstruction (nasal polyposis) and/or inflammation (allergy or chronic sinusitis) of the paranasal sinuses on nasal NO concentration was eval...

PURPOSE Nasal polyposis is a chronic inflammatory disease of the upper airways often associated with asthma and characterized by markedly increased numbers of eosinophils, Th2 type lymphocytes, fibroblasts, goblet cells and mast cells. Previous studies have shown elevated levels of thymic stromal lymphopoietin (TSLP) in atopic diseases like asthma, atopic dermatitis and mainly in animal models ...

conclusions the presence of fungi in the nasal cavity and indoors of healthy subjects in this study suggests that fungi should be considered as health hazards. furthermore, it is important and seems necessary to monitor indoor air quality and raise awareness of existing threats due to microorganisms, including fungi. results the most common fungi isolated from all samples were aspergillus, peni...