OBJECTIVE To assess the costs and cost effectiveness of phototherapy with ultraviolet B light provided at home compared with outpatient ultraviolet B phototherapy for psoriasis. DESIGN Cost utility, cost effectiveness, and cost minimisation analyses performed alongside a pragmatic randomised clinical trial (the PLUTO study) at the end of phototherapy (mean 17.6 weeks) and at one year after th...

BACKGROUND While oral psoralen plus ultraviolet A (PUVA) remains the most popular therapeutic modality for vitiligo, recent reports have shown that narrowband ultraviolet B (UVB) also induces significant repigmentation. In this study we evaluated the efficacy of broadband UVB on actively spreading, progressive vitiligo in patients who had been followed for many months (12 or more) in our practi...

espanolEl liquen escleroso es una enfermedad inflamatoria cronica, de etiologia desconocida, que afecta la piel y las mucosas. Presentamos un caso paciente con genital extragenital concomitante, presento buena respuesta al tratamiento clobetasol tracrolimus topico en region genital, fototerapia ultravioleta B banda angosta (UVB-BA) lesiones extragenitales. EnglishLichen sclerosus is a chronic i...

BACKGROUND Previous success rates of psoralen and ultraviolet A (PUVA) and narrowband UVB (NB-UVB) in the treatment of chronic urticaria are reported in few studies with no previous reports on the comparable efficacy of both modalities in the disease. AIM We aimed to compare the efficacy of PUVA versus NB-UVB in the treatment of chronic urticaria. METHODS Twenty-four patients with chronic u...

Despite strong evidence that gut microbiota can influence immunity and tumor microenvironments, the functional relationship between microbiome cutaneous T cell lymphoma (CTCL), a cancer associated with global dysbiosis, is unclear. Further, effect of narrowband UVB (nbUVB) on CTCL remains unexplored. Our team previously demonstrated patients harbor altered microbiomes their skin may carry predi...