In the title compound, C(19)H(14)ClNO(5), the aroyl group is attached to the naphthalene ring system with a non-coplanar configuration. The dihedral angle between naphthalene ring system and benzene ring is 70.62 (6)°. The nitro group is oriented in parallel with the adjacent carbonyl plane. The torsion angle of the carbonyl group and naphthalene ring is 54.68 (19)° (C-C-C-O), and that of nitro...

The bronchiolar injury/repair response to naphthalene (NA) in mice includes acute distal airway epithelial injury that is followed by epithelial proliferation and redifferentiation, which result in repair of the epithelium within 14 days. To test whether prior exposure to aged and diluted sidestream cigarette smoke (TS) would alter the injury/repair response of the airway epithelium, adult mice...

We previously reported on the denitrifier Pseudomonas stutzeri strain NAP-3 that degrades naphthalene without oxygen. In our present studies, naphthalene biodegradation by NAP-3 was slow or nearly absent when acetate was not present, suggesting a stimulating effect by the non-fermentable substrate. NAP-3 was sensitive to the amount of naphthalene in the culture; with naphthalene removal and nit...

Naphthalene, a widely used industrial and household chemical, has rarely been an agent of poisoning worldwide. Severe haemolysis from naphthalene poisoning is rare and can be a challenge to clinicians. We report a 22-year-old female, who accidentally ingested naphthalene mixed coconut oil and got admitted with recurrent vomiting, headache and passage of dark urine. Severe intravascular haemolys...

The ability of the rabbit to metabolize naphthalene and chlorinated naphthalene was markedly influenced by the degree of halogenation of the compound according to Cornish and Block (2). Naphthalene is related structurally to biphenyl, in which a coaxial linkage connecta two phenyl molecules. Whethe? the presence of a chlorine atom in biphenyl also alters the metabolism of this compound as it, d...

The research was focused on the slurry-phase biodegradation of naphthalene in soil. Among ex-situ techniques, the slurry-phase technique offers the advantage to increase the availability of contaminants to bacteria. From soil samples collected on a contaminated site, the Pseudomonas putida M8 strain capable to degrade naphthalene was selected. Experiments were performed in a stirred and oxygena...

The sulfate-reducing culture N47 can utilize naphthalene or 2-methylnaphthalene as the sole carbon source and electron donor. Here we show that the initial reaction in the naphthalene degradation pathway is a methylation to 2-methylnaphthalene which then undergoes the subsequent oxidation to the central metabolite 2-naphthoic acid, ring reduction and cleavage. Specific metabolites occurring exc...

Given that the degradation of aromatic pollutants in anaerobic environments such as sediment is generally very slow, aeration could be an efficient bioremediation option. Using stable isotope probing (SIP) coupled with pyrosequencing analysis of 16S rRNA genes, we identified naphthalene-utilizing populations in aerated polyaromatic hydrocarbon (PAH)-polluted sediment. The results showed that na...

UNLABELLED Naphthalene is a ubiquitous pollutant, and very high concentrations are sometimes encountered indoors when this chemical is used as a pest repellent or deodorant. This study describes the distribution and sources of vapor-phase naphthalene concentrations in four communities in southeast Michigan, USA. Outdoors, naphthalene was measured in the communities and at a near-road site. Indo...

PURPOSE Recent studies have indicated that certain aldose reductase inhibitors prevent the formation of cataracts in naphthalene-fed rats. The study was designed to investigate whether aldose reductase itself is involved in the metabolism of naphthalene in the lens and the mechanism of this cataract formation. METHODS Aldose reductase was purified from whole rat lens using a series of chromat...