Although nanoparticle-protein conjugates have been synthesized for numerous applications, bioconjugation remains a challenge, often resulting in denaturation or loss of protein function. This is partly because the protein-nanoparticle interface is poorly understood, which impedes the use of nanoparticles in nanomedicine. Although the effects of nanoparticle ligand and material on protein struct...

magnetic nanoparticles can bind to different drug delivery systems and can be used for drug targeting to a specific organ by using an external magnetic field as well as used in hyperthermia by heating in alternating magnetic fields. the characteristics of iron oxide nanoparticles are significantly affected by particle size, shape and zeta potential, among which the particle size plays the most ...

Biodistribution of nanoparticles is dependent on their physicochemical properties (such as size, surface charge, and surface hydrophilicity). Clear and systematic understanding of nanoparticle properties' effects on their in vivo performance is of fundamental significance in nanoparticle design, development and optimization for medical applications, and toxicity evaluation. In the present study...

Nanoparticle research has become increasingly important in the context of bioscience and biotechnology. Practical use of nanoparticles in biology has significantly advanced our understanding about biological processes in the nanoscale as well as led to many novel diagnostic and therapeutic applications. Besides, synthetic and natural nanoparticles are of concern for their potential adverse effe...

Ta/Ru/Co/Ru/Co/Cu/Co/Ni80Fe20/Ta spin-valve giant magnetoresistive (GMR) multilayers were deposited using UHV magnetron sputtering and optimized to achieve a 13% GMR ratio before patterning. The GMR multilayer was patterned into 12 sensor arrays using a combination of e-beam and optical lithographies. Arrays were constructed with 400 nm × 400 nm and 400 nm × 200 nm sensors for the detection of ...

Sound wave propagation arising from the highfrequency acoustic irradiation of a fluid can generate considerable stresses at the free surface of the fluid leading toward its destabilization and subsequent breakup. If the fluid comprises a polymer solution, the evaporation of the solvent from the aerosols that are generated as a consequence of the atomization process leaves behind a solidified po...

Nanoparticles play a crucial role in biomedical and sensing applications. In this paper the design of non-spherical gold nanoparticles, operating in the near infrared and visible regime, is proposed. The structures consist of metallic resonating inclusions of different shapes embedded in a dielectric environment. Different geometries, such as cube, elliptical cylinder and rod are considered. Th...

Magnetic field based micro/nanoelectromechanical systems (MEMS/NEMS) devices are proposed that use 10 nm diameter magnetic particles, with and without a carrier fluid, for a new class of nanoduct flows, nanomotors, nanogenerators, nanopumps, nanoactuators, and other similar nanoscale devices. A few examples of macroscopic ferrohydrodynamic instabilities that result in patterns, lines, and struc...

In an effort to translate PRINT nanoparticle fabrication from batch processes to continuous manufacturing, Liquidia Technologies has harnessed the scale of roll-to-roll processing with the precision of microlithography to enable GMP production of gram to kilogram quantities of nanoparticle based therapeutic formulations. The in-house capabilities now enable fast turnover from single wafer maste...

The use of nanoparticles as carriers for the delivery of therapeutic materials to target tissues has became popular in recent years and has demonstrated great potentials for the treatments of a wide range of diseases. In this review, we summarize the advantages of nanotechnology as a common gene delivery strategy with emphasis on ocular therapy. Particular attention is paid to the CK30-PEG comp...