Nanoscale carriers of active compounds, especially drugs, need not be spherical in shape. Worm micelles as blends of degradable polylactic acid (PLA) and inert block copolymer amphiphiles were prepared for controlled release and initial study of carrier transport through nano-porous media. The loading capacity of a typical hydrophobic drug, Triamterene, and the release of hydrophobic dyes were ...

Psoriasis is a topical disease that leads to red and scratchy skin, most commonly on the knees, elbows, trunk scalp. an inflammatory constrains, aloe-vera, natural product, reported have anti-inflammatory properties. Further, Vitamin-E has antioxidant properties it can aid protect against some of oxidative burden occurs with psoriasis. Naturally, vitamin E broad spectrum benefits for health, ha...

Herein we demonstrate that dynamic covalent chemistry can be used to induce reversible morphological transitions in block copolymer nano-objects and hydrogels. Poly(glycerol monomethacrylate)-poly(2-hydroxypropyl methacrylate) (PGMA-PHPMA) diblock copolymer nano-objects (vesicles or worms) were prepared via polymerization-induced self-assembly. Addition of 4-carboxyphenylboronic acid (CPBA) lea...

giant unilamellar vesicles (guvs) consisting in self-closed lipid bilayers of 0.5-100 µm diameter are considered as oversimplified models of cells because of their biological membrane and micrometric size while large unilamellar vesicles (luvs) of 100-500 nm diameter have applications in drug delivery. to improve structural and mechanical properties of these vesicles, we have developed two cate...

seminal vesicles (svs) are sex accessory organs and part of male genitourinary system. they play a critical role in male fertility. diseases of the svs, usually results in infertility. diseases of the svs are extremely rare and are infrequently reported in the literature. we address the current literature of sv pathologies, symptoms, diagnosis, and treatment options. we review the clinical impo...

Lipid-based photoantimicrobial supramolecular assemblies are promising structures for the development of new photodynamic treatments wound bacterial infections. Phenalenone (1H-phenalene-1-one, PN) has been used to obtain four stearoyl acid-based phenalenone derivatives (PNC18), with different types linkage and number acyl chains. After studying interfacial properties these compounds, nano-obje...

Back Cover: In article number 2000765 by San H. Thang, Anchao Feng, Zhao Wang, and co-workers, a series of well-defi ned CO2-responsive statistical, gradient block copolymer nano-objects are synthesized through batch, semi-batch stepwise reversible addition-fragmentation chain transfer (RAFT) polymerization. aqueous solution, the copolymers can self-assemble into various aggregates before CO2 s...