The emerging technology of drug-encapsulated nanoparticles plays a critical role in the development of treatment for various life-threatening diseases due to the versatility, control, and future potential of the design of these systems. A current treatment technique for the treatment of brain tumor cells, after major surgery, utilizes a drug adhered to a biodegradable polymer wafer that provide...

Over the years, researchers have attempted to improve potency of medicament utilization for treatment a variety diseases. Drug targeting is phenomenon in which drug distributed body such way that it interacts with target tissue at cellular or sub-cellular level achieve desired therapeutic response site while avoiding unwanted interactions other sites. This can be accomplished using modern deliv...

Cosmetics attract most age groups from teenagers to old age. Cosmetic goods now contain a variety of nanoparticle and nanomaterial types. Nano cosmeceuticals have changed the era cosmetics as they advanced delivery mechanisms with task specifications. They are used in nail, hair, lip, skin care products by cosmetic giants including Estee Lauder, L’oreal, Nivea, Zelens, Derma Swiss, etc., patent...

Glaucoma is a common progressive eye disorder and the treatment strategies will benefit from nanoparticulate delivery systems with high drug loading and sustained delivery of intraocular pressure lowering agents. Niosomes have been reported as a novel approach to improve drug low corneal penetration and bioavailability characteristics. Along with this, poor entrapment efficiency of hydrophilic ...

Nowdays, the design of the optimalniosomal formulation may ensure the best performance in terms of physico-chemical properties and drug skin permeation. Our study want to propose the loading of Tetracycline or Tetracycline hydrocholoride drugs as strategy to modulate niosomes properties, with particular emphasis on encapsulation and percutaneous permeation behavior. Niosomes were prepared from ...

Topical beta-blocking agents are nowadays the drugs of choice as these have few ocular and systemic side effects. In the present study some selected beta blockers (PP-24, PP-34, PP-41, PP-48, PP-50), synthesized using 4-hydroxybenzaldehyde and isovanillin were encapsulated into niosomes possessing a high drug entrapment efficiency in order to be used as ophthalmic carriers for topical ocular tr...

Niosomes are vesicular nacarriers that can be used for both amphiphilic and lipophilic drugs. budding vehicles in advanced drug delivery systems. nionic surfactants vesicles formed with or without the addition of cholesterol. best choice because their specific characters like biodegradability, biocompatibility, immugenic nature. easily trap hydrophilic drugs extend period systemic circulation. ...

In this study, different positively charged niosomal formulations containing sorbitan esters, cholesterol and cetyl trimethyl ammonium bromide were prepared by film hydration method for the entrapment of autoclaved Leishmania major (ALM). Size distribution pattern and stability of niosomes were investigated by laser light scattering method and ALM encapsulation per cent was measured by the bici...

BACKGROUND/AIM The purpose of this study was to investigate and compare the pharmacokinetic behavior and tissue distribution of paclitaxel, delivered as commercial preparation Taxol or through Span 40 niosomes, after intravenous injection to rats. MATERIALS AND METHODS Paclitaxel-loaded Span 40 niosomes were prepared using the thin-film method. An HPLC method was developed and validated for p...