Purpose: To summarize main findings of topical or transdermal preparation delivered in the skin eye region using novel nano-technology. Method: Narrative review all relevant papers from peer reviewed and high impact journals. Results: The delivery system pharmaceutical preparations for eyes are now elevated to aerosolized gels, foams, sprays other forms that nano-pharmaceutical dynamics such as...

Worldwide, influenza affects millions of individuals and has the potential to cause serious illness or even death. The most effective approach prophylaxis is vaccination, but due strain viral mutation changes, seasonal vaccine frequently limited efficiency needs be administered annually. Although they have been employed clinically, more conserved universal antigens like M2 ectodomain (M2e) hema...

This review focuses on polymer- and liposome-based nanoparticles used in targeted delivery of bioactive molecules, from drugs to siRNA to pDNA. The perspective centers around commercial and clinical successes, and a rationalization of these successes. Microparticulate systems are not covered, and only those applications that truly utilize the advantages of nano size are covered. "Stealth" syste...

Liposomes are tiny spheres ranging in diameters from 50 nm to several microns. The scope of this mini review is to introduce the concept of liposomes and to describe some aspects and mechanisms of stimulating topical and injectable products with liposomes. Two examples discussed in this article are topical delivery across skin and injectable formulations for anticancer drugs. Classic liposomes ...

Statins are effective lipid lowering agents traditionally used for the primary and secondary prevention of cardiovascular disease. Statins also exert a range of pleiotropic effects that make them attractive candidates for use in a wide range of disorders, in particular inflammatory and immune mediated conditions. However, the exploitation of such pleiotropic effects has been greatly hindered by...

Colorectal cancer (CRC) is the third most frequently occurring tumor in human population. CRCs are usually adenocarcinomatous and originate as a polyp on inner wall of colon or rectum which may become malignant due course time. Although therapeutic options CRC limited, early diagnosis play an important role preventive interventions to decrease mortality rate. The CRC-affected tissues exhibit se...

Although vaccines and antibiotics could kill or inhibit microbes, many infectious diseases remain difficult to treat because of acquired resistance and adverse side effects. Nano-carriers-based technology has made significant progress for a long time and is introducing a new paradigm in drug delivery. However, it still has some challenges like lack of specificity toward targeting the infectious...

Various types of nanoparticles, such as liposomes, polymeric micelles, dendrimers, superparamagnetic iron oxide crystals, and colloidal gold, have been employed in targeted therapies for cancer. Both passive and active targeting strategies can be utilized for nano-drug delivery. Passive targeting is based on the enhanced permeability and retention (EPR) effect of the vasculature surrounding tum...

Cancers are a leading cause of death today as they will be in the future. Chemotherapy is one of the major weapons we have in the ill equipped battle against this important human threat. Despite several drawbacks, nanoparticle based drug delivery systems (DDS) hold promise to ameliorate anticancer chemotherapy. From the beginning of “Nano medicine” by the discovery of liposomes by Bangham et al...

Fish oils have many dietary benefits, but due to their strong odors and rapid deterioration, their application in food formulations is limited. For these reasons, nano-liposome was used to nano-encapsulate fish oil in this study and encapsulated fish oil was utilized in fortifying yogurt. Physicochemical properties of produced yogurt including pH, acidity, syneresis, fatty acid composition, per...