The selective nitrosation of β-dicarbonyl compounds with sodium nitrite was carried out under1-methyl-3-carboxymethylimidazolium chloride, prepared from N-methylimidazole andchloroacetic acid, as an acidic ionic liquid. The reaction was found to proceed under relativelymild conditions with excellent conversion and selectivity. The ionic liquid was recycled andreused.

In this contribution we present an overview on the relation between the complex structure of ionic liquids (ILs) and its impact in the field of surface science. The results herein described result mainly from modeling and simulation work carried out at Centro de Química Estrutural, Universidade de Lisboa, complemented in some cases by experimental results obtained at Instituto de Tecnologia Quí...

Room-temperature ionic liquid (RTIL) has been widely investigated as a nonvolatile solvent as well as a unique liquid material because of its interesting features, e.g., negligible vapor pressure and high thermal stability. Here we report that a non-volatile polymerizable RTIL is a useful starting material for the fabrication of micro/nano-scale polymer structures with a focused-ion-beam (FIB) ...

The Brønsted acidic ionic liquid ([BMIm]HSO4) catalyzed three-component synthesis of 2H-indazolo[2,1-b]phthalazine-trione derivatives at room temperature. The integrity of the ionic liquid remains reasonably unchanged when it is separated from the reaction mixture by water extraction, as it can be recycled several times without any loss of activity in each of the title syntheses. The products a...

In this research, a green, operationally simple, highly efficient and facile cascade Biginelli reaction using various aromatic aldehydes, ethyl acetoacetate, and urea/thiourea has been developed. First, the ionic liquid was prepared from the reaction of 1-methyl-2-pyrolidone with methane sulfonic acid. Then, this ionic liquid was applied as an acidic catalyst in the synthesis of dihydropyrimidi...

In this research, various polycyclic fused acridines were synthesized via the highly efficient and green one-step four-component reaction between isatins, dimedone, various amines, and dimethylacetylenedicarboxylates (DMAD/DEAD) in the presence of n-octyl-3-methylpipyridinium bromide ([OMePPy]+Br-) as a newly prepared ionic liquid, in absolute green situations at room temperature under solvent-...

Electrospinning is a versatile process used to prepare micro- and nano- sized fibers from various polymers dissolved in volatile solvents. In this report, cellulose and cellulose-heparin composite fibers are prepared from nonvolatile room temperature ionic liquid (RTIL) solvents by electrospinning. RTILs are extracted from the biopolymer fiber after the fiber formation using a cosolvent. Micron...

α-Amino nitriles are synthesized in a one-pot, three-component coupling of aldehydes (or ketones), aniline, and trimethylsilyl cyanide using a catalytic amount of choline chloride.2ZnCl2 as a bio Lewis acidic ionic liquid. Mild Lewis acidic characteristic of this ionic liquid allows efficient synthesis of α-amino nitriles from acid sensitive aldehydes.

For the first time, a novel and efficient ionic liquid-based ultrasound-assisted in-situ solvent formation microextraction (IL-UA-ISFME) combined with high-performance liquid chromatography-ultraviolet detection (HPLC-UV) has been successfully developed for the determination of duloxetine (DLX) in human plasma. Herein, an environmentally-friendly hydrophobic ionic liquid (1-butyl-3-methylimidaz...

In this study, we combined Ionic Liquid-based Dispersive Liquid Liquid Micro Extraction (IL-DLLME) with FAAS for determining the palladium in different real samples at the trace level. 1-hexyl-3-methylimidazolium hexafluorophosphate [Hmim][PF6] ionic liquid and 1-(2-pyridylazo) 2-naphthol (PAN), were chosen as the extraction solvent and the chelating agent, respectively. The hydr...