Acoustic sensitivity of the vestibular apparatus is well-established, but the contribution of vestibular receptors to the late auditory evoked potentials of cortical origin is unknown. Evoked potentials from 500 Hz tone pips were recorded using 70 channel EEG at several intensities below and above the vestibular acoustic threshold, as determined by vestibular evoked myogenic potentials (VEMPs)....

UNLABELLED In children with cochlear implant (CI), the recording of the electrically evoked compound action potential (ECAP) of the auditory nerve represents an option to assess changes in auditory nerve responses and the interaction between the electrode bundle and the neural tissue over time. AIM To study ECAP in children during the first year of CI use. MATERIALS AND METHODS The ECAP cha...

Event-related potentials (ERPs) were recorded from volunteers performing a task requiring simple judgements about the spatial location of a single target that could appear with equal probability to the left or right of fixation. A robust finding in the ERP literature is a dichotomy between attentional selection for spatial and non-spatial features. Visual spatial selection is manifest as a modu...

Cortical cross-modal re-organization, or recruitment of auditory cortical areas for visual processing, has been well-documented in deafness. However, the degree of sensory deprivation necessary to induce such cortical plasticity remains unclear. We recorded visual evoked potentials (VEP) using high-density electroencephalography in nine persons with adult-onset mild-moderate hearing loss and ei...

In children with cochlear implant (CI), the recording of the electrically evoked compound action potential (ECAP) of the auditory nerve represents an option to assess changes in auditory nerve responses and the interaction between the electrode bundle and the neural tissue over time. Aim: To study ECAP in children during the first year of CI use. Materials and methods: The ECAP characteristics ...

To explore the potential involvement of aberrant Notch1 signaling in breast cancer pathogenesis, we have used a transgenic mouse model. In these animals, mouse mammary tumor virus LTR-driven expression of the constitutively active intracellular domain of the Notch1 receptor (N1(IC)) causes development of lactation-dependent mammary tumors that regress upon gland involution but progress to nonre...

Studies of visual cortical responses following visual perceptual learning (VPL) have produced diverse results, revealing neural changes in early and/or higher-level visual cortex as well as changes in regions responsible for higher cognitive processes such as attentional control. In this study, we investigated substrates of VPL in the human brain by recording visual evoked potentials with high-...

UNLABELLED Long latency auditory evoked potentials (LLAEP) alterations in individuals with tinnitus are suggestive of dysfunction in the central auditory pathways at a cortical level. AIM To characterize the LLAEP in individuals with and without tinnitus exposed to occupational noise. METHOD Cross-sectional contemporary cohort, prospective study. Sixty subjects exposed to occupational noise...

BACKGROUND The exact cerebral structural and functional mechanisms under the auditory verbal hallucinations (AVHs) in schizophrenia are still unclear. The Deutsch "high-low" word illusion might trigger attentional responses mimicking those under AVHs. METHODS We therefore have invited 16 patients with first-episode, paranoid schizophrenia, and 16 age- and gender-matched healthy volunteers to ...

Speech perception, especially in noise, may be maximized if the perceiver observes the naturally occurring visual-plus-auditory cues inherent in the production of spoken language. Evidence is conflicting, however, about which aspects of visual information mediate enhanced speech perception in noise. For this reason, we investigated the relative contributions of audibility and the type of visual...