نتایج جستجو برای: n 43
تعداد نتایج: 1053784 فیلتر نتایج به سال:
Objetivo: Determinar los condicionantes de salud del estilo vida y capacidad funcional adultos mayores atendidos en una Microred Ica, Perú 2021. Materiales Métodos: Estudio cuantitativo, descriptivo transversal, con muestra 94 mayores. Se utilizaron como instrumentos el Cuestionario Índice Barthel, se aplicaron medidas tendencia central, uso frecuencias análisis porcentual. Resultados: encuesta...
BACKGROUND Prolonged labour is associated with greater morbidity and mortality for mother and child. Connexin 43 is a major myometrial gap junction protein found in human myometrium. Syndecan 3 seems to prevail in the human uterus among heparan sulphate proteoglycans, showing the most significant increase during labour. The aims of the present study were to investigate syndecan 3 and connexin 4...
Sorafenib is a multiple kinase inhibitor which targets Raf kinases, VEGFR, and PDGFR and is approved for the treatment of hepatocellular carcinoma (HCC). Previously, we found that p-STAT3 is a major target of SC-43, a sorafenib derivative. In this study, we report that SC-43-induced apoptosis in cholangiocarcinoma (CCA) via a novel mechanism. Three CCA cell lines (HuCCT-1, KKU-100 and CGCCA) we...
We identify a new amyloidogenic peptide from the glutamine/asparagine-rich region of the FTLD-related protein (TDP-43), which can seed both the full-length and N-terminus-truncated TDP-43. Through the microinjection and real-time fluorescence imaging, we also found that this novel peptide could trigger cell apoptosis and initiate TDP-43 aggregation in the cytosol.
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