BACKGROUND Myocardial injury is a common complication during cardiac surgery and percutaneous coronary intervention and is associated with postprocedural cardiovascular morbidity and mortality. Limited data have been reported about the occurrence of myocardial damage associated with transcatheter aortic valve implantation (TAVI). Therefore, our purpose was to investigate the incidence, predicto...

Myocardial ischemia-reperfusion injury is one of the most common cardiovascular diseases, and can lead to serious damage and dysfunction of the myocardial tissue. Previous studies have demonstrated that berberine exhibits ameliorative effects on cardiovascular disease. The present study further investigated the efficacy and potential mechanism underlying the effects of berberine on ischemia-rep...

Sex hormones are important modifiers of the acute inflammatory response to injury, an important aspect of myocardial depression and apoptosis following ischemia or endotoxemia. Hemorrhage, trauma, ischemia/reperfusion, burn and sepsis each lead to cardiac dysfunction. Gender has been shown to influence the inflammatory response as well as outcomes following acute injury. The mechanisms by which...

BACKGROUND Myocardial and renal injury commonly contribute to perioperative morbidity and mortality after abdominal aortic aneurysm repair. Remote ischemic preconditioning (RIPC) is a phenomenon whereby brief periods of ischemia followed by reperfusion in one organ provide systemic protection from prolonged ischemia. To investigate whether remote preconditioning reduces the incidence of myocard...

Myocardial injury is common in patients without acute coronary syndrome, and international guidelines recommend patients with myocardial infarction are classified by aetiology. The universal definition differentiates patients with myocardial infarction due to plaque rupture (type 1) from those due to myocardial oxygen supply-demand imbalance (type 2) secondary to other acute illnesses. Patients...

Since the emergence of novel coronavirus 2019 disease (COVID-19), cardiovascular impairment and alterations in cardiology laboratory tests suggestive myocardial injury, even patients without symptoms, have been observed hospitalized children adults.– Epidemiological data from China suggested that cardiac injury may occur 19% to 28% with COVID-19. Several factors seem contribute damage, potentia...

the results obtained in the present investigations point to a definite correlation between the onset of myocardial injury, electrocardiographic changes and biochemical changes. changes in the electrocardiogram and elevated serum levels were paralleled by an increased excretion of magnesium in urine as early as one hour. serum calcium and serum potassium levels did not show any significant resul...

Naoxintong (NXT) is a Chinese Materia Medica standardized product extracted from 16 various kinds of Chinese traditional herbal medicines including Salvia miltiorrhiza, Angelica sinensis, Astragali Radix. Naoxintong is clinically effective in treating ischaemia heart disease. Nucleotide-binding oligomerization domain-Like Receptor with a Pyrin domain 3 (NLRP3) inflammasome has been critically i...

Myocardial ischemia and reperfusion (I/R) injury is well known in therapy for acute coronary syndrome and open heart surgery. Although reperfusion therapy (such as thrombolysis and percutaneous coronary intervention) is essential for the survival of ischemic tissue, reperfusion itself causes additional cellular injury. I/R could cause local myocardial inflammation, accompanying with apoptosis, ...