Botulinum toxin inhibits acetylcholine release and therefore could cause mydriasis. We report a case of acute angle-closure glaucoma which occurred shortly after a series of injections of botulinum toxin round the eyelids for blepharospasm.

Cataract surgery is performed more easily if mydriasis can be maintained until the intraocular lens has been inserted. Intraocular irrigation with adrenaline is thought to be of benefit in this respect, and is used by some surgeons but not others. This prospective double blind controlled trial assessed the efficacy and safety of using perioperative adrenaline during extracapsular cataract surge...

Anisocoria, or unequal pupil size, may be an early sign of an impending neurologic emergency in any patient.1 Acute unilateral mydriasis is often suggestive of a lifethreatening condition affecting cranial nerve function, such as tumor compression, intracranial hypertension with impending uncal herniation, expanding intracranial aneurysm, or hemorrhage. Benign mydriasis can be due to prior trau...

Lupinus mutabilis (LM) is a widespread species of lupin whose bean is consumed not only for its high caloric value but also as a homeopathic medicine, used for a diverse range of presumed clinical properties, including as an analgesic and an antidiabetic. The properties of lupine alkaloids are responsible for their anticholinergic toxicity in both the autonomic nervous system and the central ne...

BACKGROUND/AIMS Well dilated pupils make eye surgery easier. A classic twin study was established to examine the relative importance of genes and environment in the variance of pupil size after mydriasis, and to examine the effects of other factors such as age, iris colour, and refractive error. METHODS 506 twin pairs, 226 monozygotic (MZ) and 280 dizygotic (DZ), aged 49-79 (mean age 62.2 yea...

Background/aims—Well dilated pupils make eye surgery easier. A classic twin study was established to examine the relative importance of genes and environment in the variance of pupil size after mydriasis, and to examine the eVects of other factors such as age, iris colour, and refractive error. Methods—506 twin pairs, 226 monozygotic (MZ) and 280 dizygotic (DZ), aged 49–79 (mean age 62.2 years,...